Abstract
Extraneural metastases of glioblastoma multiforme (GBM) are a relatively rare occurrence which usually manifest after de novo GBM. We report a case of a patient with an oligodendroastrocytoma who developed over a period of 12 years malignant progression to glioblastoma followed by multiple cytologically confirmed bone metastases. No 1p deletions were detected in the original tumour. GBM cells disclosed the EGFr(+) and p53(−) immunophenotype more characteristic of a primary GBM.
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Cervio, A., Piedimonte, F., Salaberry, J. et al. Bone Metastases from Secondary Glioblastoma Multiforme: A Case Report. J Neurooncol 52, 141–148 (2001). https://doi.org/10.1023/A:1010629618859
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DOI: https://doi.org/10.1023/A:1010629618859