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Properties of 8-Cyano-5-phenyl-7-trifluoromethyl-2,3-dihydroimidazo[1,2-a]pyridines

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Abstract

The alkylation, acylation, halogenation, nitration, oxidation, and hydrolysis reactions of 8-cyano-5-phenyl-7-trifluoromethyl-2,3-dihydroimidazo[1,2-a]pyridine have been studied. It was found that the 6-halo derivatives add alcohol to give covalent solvates. X-ray analysis has been carried out on one of the solvates (6-chloro-8-cyano-7-ethoxy-5-phenyl-7-trifluoromethyl-1,2,3,7-tetrahydroimidazo[1,2-a]pyridine) as well as on 8-cyano-5-phenyl-7-trifluoromethyl-2,3-dihydroimidazo[1,2-a]pyridine trifluoroacetate.

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Authors and Affiliations

  1. Riga Technical University, Riga, LV-1048, Latvia

    J. Suloeva, M. Jure, E. Gudriniece & M. Petrova

  2. Latvian Institute of Organic Synthesis, Riga, LV-1006, Latvia

    A. Kemme

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  1. J. Suloeva
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  2. M. Jure
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  3. E. Gudriniece
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  4. M. Petrova
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  5. A. Kemme
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Suloeva, J., Jure, M., Gudriniece, E. et al. Properties of 8-Cyano-5-phenyl-7-trifluoromethyl-2,3-dihydroimidazo[1,2-a]pyridines. Chemistry of Heterocyclic Compounds 38, 714–729 (2002). https://doi.org/10.1023/A:1019977505210

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  • DOI: https://doi.org/10.1023/A:1019977505210

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