Douglas N, Polo O. Pathogenesis of obstructive sleep apnoea/hypopnea syndrome. Lancet. 1994;344:653–5.
Article
CAS
PubMed
Google Scholar
Deegan P, McNicholas W. Pathophysiology of obstructive sleep apnoea. Eur Respir J. 1995;8:1161–78.
Article
CAS
PubMed
Google Scholar
Berry R, Budhiraja R, Gottlieb D, et al. Rules for scoring respiratory events in sleep: update on the 2007 AASM manual for the scoring of sleep and associated events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med. 2010;8:597–619.
Google Scholar
Schwab R, Kuna S, Remmers J. Anatomy and physiology of upper airway obstruction. In: Kryger MH, Roth T, Dement WC, editors. Principles and practice of sleep medicine. Philadelphia: Elsevier Saunders; 2005. p. 983–93.
Chapter
Google Scholar
Guilleminault C, Akhtar F. Pediatric sleep-disordered breathing: new evidence on its development. Sleep Med Rev. 2014;24:46–56.
Article
PubMed
Google Scholar
Kim AM, Keenan BT, Jackson N, et al. Tongue fat and its relationship to obstructive sleep apnea. Sleep. 2014;37:1639–48.
PubMed Central
PubMed
Google Scholar
Eckert K, Malhotra A. Pathophysiology of adult obstructive sleep apnea. Proc Am Thorac Soc. 2008;5:144–53.
PubMed Central
Article
PubMed
Google Scholar
Malhotra A, Huang Y, Fogel R, Lazic S, Pillar G, Jakab M. Aging influences on pharyngeal anatomy and physiology: the predisposition to pharyngeal collapse. Am J Med. 2006;119:72.e9–72.14.
Peppard P, Young T, Barnet J, et al. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol. 2013;177:1006–14.
PubMed Central
Article
PubMed
Google Scholar
Stores G. Clinical diagnosis and misdiagnosis of sleep disorders. J Neurol Neurosurg Psychiatry. 2007;78:1293–7.
PubMed Central
Article
CAS
PubMed
Google Scholar
George C. Sleep apnea, alertness, and motor vehicle crashes. Am J Respir Crit Care Med. 2007;10:954–6.
Article
Google Scholar
Aydin M, Altin R, Oeren A, Kart L, Bilge M, Unalacak M. Cardiac autonomic activity in obstructive sleep apnea: time-dependent and spectral analysis of heart rate variability using 24-hour Holter electrocardiograms. Tex Heart Inst J. 2004;31:132–6.
PubMed Central
PubMed
Google Scholar
Foster G, Poulin M, Hanley P. Intermittent hypoxia and vascular function: implications for obstructive sleep apnoea. Exp Physiol. 2007;92:51–65.
Article
PubMed
Google Scholar
Lurie A. Endothelial dysfunction in adults with obstructive sleep apnea. Adv Cardiol. 2011;46:139–70.
Article
PubMed
Google Scholar
Somers VK, White DP, Amin R, et al. Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation scientific statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing. Circulation. 2008;118:1080–111.
Article
PubMed
Google Scholar
Oga T, Chin K, Tabuchi A, et al. Effects of obstructive sleep apnea with intermittent hypoxia on platelet aggregability. J Atheroscler Thromb. 2009;16:862–9.
Article
PubMed
Google Scholar
Peppard P, Young T, Palta M, Skaturd J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med. 2000;342:1378–84.
Article
CAS
PubMed
Google Scholar
Guilleminault C, Connoly S, Winkle R. Cardiac arrhythmia and conduction disturbances during sleep in 400 patients with sleep apnea syndrome. Am J Cardiol. 1983;52:490–4.
Article
CAS
PubMed
Google Scholar
Bazan V, Grau N, Valles E, et al. Obstructive sleep apnea in patients with typical atrial flutter: prevalence and impact on arrhythmia control outcome. Chest. 2013;143:1277–83.
Article
PubMed
Google Scholar
Cami A, Howard D, Olson E, Somers V. Day-night pattern of sudden death in obstructive sleep apnea. N Engl J Med. 2005;352:1206–14.
Article
Google Scholar
Marin J, Carrizo S, Vicente E, Agusti A. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet. 2005;365:1046–53.
Article
PubMed
Google Scholar
Chervin R. Sleepiness, fatigue, tiredness, and lack of energy in obstructive sleep apnea. Chest. 2000;118:372–9.
Article
CAS
PubMed
Google Scholar
Tomfohr L, Ancoli-Israel S, Loredo J, Dimsdale J. Effects of continuous positive airway pressure on fatigue and sleepiness in patients with obstructive sleep apnea: data from a randomized controlled trial. Sleep. 2001;34:121–6.
Google Scholar
Findley L, Barth J, Powers D, Wilhoit S, Bod D, Suratt P. Cognitive impairment in patients with obstructive sleep apnea and associated hypoxemia. Chest. 1986;90:686–90.
Article
CAS
PubMed
Google Scholar
Saunamaki T, Jehkonen M. A review of executive functions in obstructive sleep apnea syndrome. Acta Neurol Scand. 2007;115:1–11.
Article
CAS
PubMed
Google Scholar
Beebe D, Gozal D. Obstructive sleep apnea and the pre-frontal cortex: towards a comprehensive model linking nocturnal upper airway obstruction to daytime cognitive and behavioural deficits. J Sleep Res. 2002;11:1–16.
Article
PubMed
Google Scholar
Naegele B, Thouvard V, Pepin J, et al. Deficits of cognitive executive functions in patients with sleep apnea syndrome. Sleep. 1995;18:43–52.
CAS
PubMed
Google Scholar
Sedky K, Bennet D, Carvalho K. Attention deficit hyperactivity disorder and sleep disordered breathing in pediatric populations: a meta-analysis. Sleep Med Rev. 2014;18:349–56.
Article
PubMed
Google Scholar
Yaffe K, Laffan A, Harrison S, et al. Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women. JAMA. 2001;306:613–9.
Google Scholar
Cooke J, Ayalon L, Palmer B, et al. Sustained use of CPAP slows deterioration of cognition, sleep, and mood in patients with Alzheimer’s disease and obstructive sleep apnea: a preliminary study. J Clin Sleep Med. 2009;5:305–9.
PubMed Central
PubMed
Google Scholar
Peppard P, Szklo-Coxe M, Hla K, Young T. Longitudinal association of sleep-related breathing disorder and depression. Arch Intern Med. 2006;166:1709–19.
Article
PubMed
Google Scholar
Hayley A, Williams L, Venugopal K, Kennedy G, Berk M, Pasco J. The relationships between insomnia, sleep apnoea and depression: findings from the American National Health and Nutrition Examination Survey, 2005–2008. Aust N Z J Psychiatry. 2015;49:156–70.
Article
PubMed
Google Scholar
Kawahara S, Akashiba T, Akahoshi T, Horie T. Nasal CPAP improves the quality of life and lessens the depressive symptoms in patients with obstructive sleep apnea syndrome. Intern Med. 2005;44:422–7.
Article
PubMed
Google Scholar
Gagnadoux F, Le Vaillant M, Goupil F, et al. Depressive symptoms before and after long-term CPAP therapy in patients with sleep apnea. Chest. 2014;145:1025–31.
Article
PubMed
Google Scholar
Mieczkowski B, Ezzie ME. Update on obstructive sleep apnea and its relation to COPD. Int J Chron Obstruct Pulmon Dis. 2014;9:349–62.
PubMed Central
PubMed
Google Scholar
Ip M, Lam B, Ng M, Lam W, Tsang K, Lam K. Obstructive sleep apnea is independently associated with insulin resistance. Am J Respir Crit Care Med. 2002;165:670–6.
Article
PubMed
Google Scholar
Baburao A, Souza G. Insulin resistance in moderate to severe obstructive sleep apnea in nondiabetics and its response to continuous positive airway pressure treatment. N Am J Med Sci. 2014;6:500–4.
PubMed Central
Article
PubMed
Google Scholar
Chen L, Pei J, Chen H. Effects of continuous positive airway pressure treatment on glycaemic control and insulin sensitivity in patients with obstructive sleep apnoea and type 2 diabetes: a meta-analysis. Arch Med Sci. 2014;10:637–42.
PubMed Central
Article
CAS
PubMed
Google Scholar
Vgontzas A, Papanicolaou D, Bixler E, et al. Sleep apnea and daytime sleepiness and fatigue: relation to visceral obesity, insulin resistance, and hypercytokinemia. J Clin Endocrinol Metab. 2000;85:1151–8.
Article
CAS
PubMed
Google Scholar
Lin C, Hu C, Ho J, Chiu H, Lin H. Obstructive sleep apnea and increased risk of glaucoma: a population-based matched-cohort study. Ophthalmology. 2013;120:1559–64.
Article
PubMed
Google Scholar
Hashim S, Al Mansouri F, Farouk M, Al Hashemi A, Singh R. Prevalence of glaucoma in patients with moderate to severe obstructive sleep apnea: Ocular morbidity and outcomes in a 3 year follow-up study. Eye (Lond). 2014;28:1304–9.
Article
CAS
Google Scholar
Aptel F, Chiquet C, Tamisier R, et al. Association between glaucoma and sleep apnea in a large French multicenter prospective cohort. Sleep Med. 2014;15:576–81.
Article
PubMed
Google Scholar
McNab A. Floppy eyelid syndrome and obstructive sleep apnea. Ophthal Plast Reconstr Surg. 1997;13:98–114.
Article
CAS
PubMed
Google Scholar
Robert PY, Adenis JP, Tapie P, et al. Eyelid hyperlaxity and obstructive sleep apnea (O.S.A.) syndrome. Eur J Ophthalmol. 1997;7:211–5.
CAS
PubMed
Google Scholar
Mojon DS, Hedges TR, Ehrenberg B, et al. Association between sleep apnea syndrome and nonarteritic anterior ischemic optic neuropathy. Arch Ophthamol. 2002;120:601–5.
Article
Google Scholar
Li J, McGwin G, Vaphiades MS, Owsley C. Non-arteritic anterior ischemic optic neuropathy and presumed sleep apnea syndrome screened by the sleep apnea scale of the sleep disorders questionnaire (SA-SDQ). Br J Ophthalmol. 2007;91:1524–7.
PubMed Central
Article
PubMed
Google Scholar
Purvin V, Kawasaki A, Yee R. Papilledema and obstructive sleep apnea syndrome. Arch Ophthalmol. 2000;118:1626–30.
Article
CAS
PubMed
Google Scholar
Epstein L, Kristo D, Strollo P, et al. Clinical guideline for the evaluation, management, and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med. 2009;5:263–76.
PubMed
Google Scholar
Sullivan CE, Issa FG, Berthon-Jones M, Eves L. Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares. Lancet. 1981;1:862–5.
Article
CAS
PubMed
Google Scholar
Goel A, Talwar D, Jain S. Evaluation of short-term use of nocturnal nasal continuous positive airway pressure for a clinical profile and exercise capacity in adult patients with obstructive sleep apnea-hypopnea syndrome. Lung India. 2015;32:225–32.
PubMed Central
Article
PubMed
Google Scholar
Weaver TE, Maislin G, Dinges DF, et al. Relationship between hours of CPAP use and achieving normal levels of sleepiness and daily functioning. Sleep. 2007;30:711–9.
PubMed Central
PubMed
Google Scholar
Balk E, Moorthy D, Obadan NO, et al. Diagnosis and treatment of obstructive sleep apnea in adults. Comparative Effectiveness Reviews. 2011;32.
Rizzi CF, Ferraz MB, Poyares D, Tufik S. Quality-adjusted life-years gain and health status in patients with OSAS after one year of continuous positive airway pressure use. Sleep. 2014;37:1963–8.
PubMed Central
PubMed
Google Scholar
Ip S, D’Ambrosio C, Patel K et al. Auto-titrating versus fixed continuous positive airway pressure for the treatment of obstructive sleep apnea: a systematic review with meta-analyses. Syst Rev. 2012;10:1–24.
Sawyer AM, Gooneratne N, Marcus CL, Ofer D, Richards KC, Weaver TE. A systematic review of CPAP adherence across age groups: clinical and empiric insights for developing CPAP adherence interventions. Sleep Med Rev. 2011;15:343–56.
PubMed Central
Article
PubMed
Google Scholar
Toh ST, Lin CH, Guilleminault C. Usage of 4-phase high resolution rhinomanometry and measurement of nasal resistance in sleep-disordered breathing. Laryngoscope. 2012;122:2343–9.
Article
PubMed
Google Scholar
Marcus C, Brooks L, Draper K, et al. Clinical practice guideline: diagnosis and management of obstructive sleep apnea syndrome. Pediatrics. 2012;130:576–84.
Article
PubMed
Google Scholar
Xiong Y, Yi H, Yin S, et al. Predictors of surgical outcomes of uvulopalatopharyngoplasty for obstructive sleep apnea hypopnea syndrome. Otolaryngol Head Neck Surg. 2011;145:1049–54.
Article
PubMed
Google Scholar
Holty J, Guilleminault C. Maxillomandibular advancement for the treatment of obstructive sleep apnea: a systematic review and meta-analysis. Sleep Med Rev. 2010;14:287–97.
Article
PubMed
Google Scholar
Baratieri C, Alves M, Mattos C, Lau G, Nojima L, de Souza M. Transverse effects on the nasomaxillary complex one year after rapid maxillary expansion as the only intervention: a controlled study. Dent Press J Orthod. 2014;19:79–87.
Article
Google Scholar
Pirelli P, Saponara M, Guilleminault C. Rapid maxillary expansion (RME) for pediatric obstructive apnea: a 12-year follow-up. Sleep Med. 2015;16:933–5.
Article
PubMed
Google Scholar
Vinha P, Eckeli A, Faria A, Xavier S, Mello-Filho F. Effects of surgically assisted rapid maxillary expansion on obstructive sleep apnea and daytime sleepiness. Sleep Breath. 2015;1–8. doi:10.1007/s11325-015-1214-y.
Schmidt-Nowara WW, Meade TE, Hays MB. Treatment of snoring and obstructive sleep apnea with a dental orthosis. Chest. 1991;99:1378–85.
Article
CAS
PubMed
Google Scholar
Mehta A, Qian J, Petocz P, Darendeliler M, Cistuli P. A randomized, controlled study of a mandibular advancement splint for obstructive sleep apnea. Am J Respir Crit Care Med. 2001;163:1457–61.
Article
CAS
PubMed
Google Scholar
Gotsopoulos H, Chen C, Qian J, Cistulli PA. Oral appliance therapy improves symptoms in obstructive sleep apnea: a randomized, controlled trial. Am J Respir Crit Care Med. 2002;166:743–8.
Article
PubMed
Google Scholar
Fritsch K, Iseli A, Russi E, Bloch K. Side effects of mandibular advancement devices for sleep apnea treatment. Am J Respir Crit Care Med. 2001;64:813–8.
Article
Google Scholar
Peppard P, Young T, Palta M, Dempsey J, Skaturd J. Longitudinal study of moderate weight change and sleep-disordered breathing. JAMA. 2000;284:3015–21.
Article
CAS
PubMed
Google Scholar
Fredheim JM, Rollheim J, Sandbu R, et al. Obstructive sleep apnea after weight loss: a clinical trial comparing gastric bypass and intensive lifestyle intervention. J Clin Sleep Med. 2013;9:427–32.
PubMed Central
PubMed
Google Scholar
Rogers A. Exercises for the development of the muscles of the face, with a view to increasing their functional activity. Dent Cosm. 1918;60:857–76.
Google Scholar
Guimaraes K, Drager L, Genta P, Marcondes B, Lorenzi-Filho G. Effects of oropharyngeal exercises on patients with moderate obstructive sleep apnea syndrome. Am J Respir Crit Care Med. 2009;179:962–6.
Article
PubMed
Google Scholar
Guilleminault C, Huang Y, Monteyrol P, Sato R, Quo S, Lin C. Critical role of myofascial reeducation in pediatric sleep-disordered breating. Sleep Med. 2013;14:518–25.
Article
CAS
PubMed
Google Scholar
Suzuki H, Watanabe A, Akihiro Y, et al. Pilot study to assess the potential of oral myofunctional therapy for improving respiration during sleep. J Prosthodont Res. 2013;57:195–9.
Article
PubMed
Google Scholar
Camacho M, Certal V, Abdullatif J, et al. Myofunctional therapy to treat obstructive sleep apnea: a systematic review and meta-analysis. Sleep. 2015;38:669–75.
PubMed Central
PubMed
Google Scholar
Guilleminault C, Powell N, Bowman B, Stoohs R. The effect of electrical stimulation on obstructive sleep apnea syndrome. Chest. 1995;107:67–73.
Article
CAS
PubMed
Google Scholar
Oliven A, Tov N, Geitini L, et al. Effect of genioglossus contraction on pharyngeal lumen and airflow in sleep apnoea patients. Eur Respir J. 2007;30:748–58.
Article
CAS
PubMed
Google Scholar
Certal V, Zaghi S, Riaz M, et al. Hypoglossal nerve stimulation in the treatment of obstructive sleep apnea: a systematic review and meta-analysis. Laryngoscope. 2015;125:1254–64.
Article
PubMed
Google Scholar