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γ-Alumina Catalyzed Green Synthesis of Pyran’s Annulated Heterocyclic Systems via Three-Component Reaction

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Abstract

γ-Alumina was found as a new efficient heterogeneous catalyst for the synthesis of pyran’s annulated heterocyclic systems. Three-component reaction of various aromatic aldehydes, malononitrile and cyclic CH-acids in the presence of γ-alumina in H2O as a green solvent at 50 °C gave pyran derivatives in high yields. γ-Alumina has some advantages such as cheap, available and recyclable.

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Acknowledgments

We gratefully acknowledge financial support from the Research Council of Tabriz Branch of Islamic Azad University.

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Authors and Affiliations

  1. Department of Chemistry, Tabriz Branch, Islamic Azad University, P. O. Box 1655, Tabriz, Iran

    L. Edjlali & R. Hosseinzdeh-Khanmiri

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  1. L. Edjlali
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  2. R. Hosseinzdeh-Khanmiri
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Correspondence to L. Edjlali.

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Edjlali, L., Hosseinzdeh-Khanmiri, R. γ-Alumina Catalyzed Green Synthesis of Pyran’s Annulated Heterocyclic Systems via Three-Component Reaction. Iran. J. Sci. Technol. Trans. Sci. 40, 151–156 (2016). https://doi.org/10.1007/s40995-016-0014-y

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  • DOI: https://doi.org/10.1007/s40995-016-0014-y

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