Abstract
Background
Solitary fibrous tumors of the liver (SFTL) are rare neoplasms, whose identification and definition of malignant potential are challenging.
Case presentation
A 62-year-old patient underwent conventional imaging and CEUS to characterize an indeterminate liver lesion after other imaging techniques were inconclusive. In fact, all diagnostic techniques concluded that it was a partially fibrotic lesion, while CEUS determined its extra-hepatocellular origin and malignant potential, initially hypothesized to be a cholangiocarcinoma. Due to the possible risk of seeding following a biopsy procedure, the patient was a candidate for surgery. Subsequently, histopathological examination revealed SFTL.
Conclusion
CEUS confidently characterized the malignancy and hypothesized the origin of the liver lesion, thus aiding in treatment planning.
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Abbreviations
- SFT:
-
Solitary fibrous tumor
- SFTL:
-
Solitary fibrous tumor of the liver
- y.o.:
-
Years old
- CEUS:
-
Contrast-enhanced US
- MRI:
-
Magnetic resonance imaging
- CT:
-
Computerized tomography
References
Lu C, Ji Y, Shan F, Guo W, Ding J, Ge D (2008) Solitary fibrous tumor of the pleura: an analysis of 13 cases. World J Surg agosto 32(8):1663–1668
Santeusanio G, Schiaroli S, Ortenzi A, Mulè A, Perrone G, Fadda G (2008) Solitary fibrous tumour of thyroid: report of two cases with immunohistochemical features and literature review. Head Neck Pathol 2(3):231–5
Ho YH, Yap WM, Chuah KL (2010) Solitary fibrous tumor of the adrenal gland with unusual immunophenotype: a potential diagnostic problem and a brief review of endocrine organ solitary fibrous tumor. Endocr Pathol 21(2):125–9
Rhee SJ, Ryu JK, Han SA, Won KY (2016) Solitary fibrous tumor of the breast: a case report and review of the literature. J Med Ultrason 43(1):125–8
Chen N, Slater K (2017) Solitary fibrous tumour of the liver—report on metastasis and local recurrence of a malignant case and review of literature. World J Surg Oncol dicembre 15(1):27
Famà F, Bouc YL, Barrande G, Villeneuve A, Berry MG, Pidoto RR et al (2008) Solitary fibrous tumour of the liver with IGF-II-related hypoglycaemia A case report. Langenbecks Arch Surg 393(4):611–6
Fuksbrumer MS, Klimstra D, Panicek DM (2000) Solitary fibrous tumor of the liver: imaging findings. AJR Am J Roentgenol 175(6):1683–7. https://doi.org/10.2214/ajr.175.6.1751683. PMID: 11090404
Martin-Broto J, Mondaza-Hernandez JL, Moura DS, Hindi N (2021) A comprehensive review on solitary fibrous tumor: new insights for new horizons. Cancers gennaio 13(12):2913
Makino Y, Miyazaki M, Shigekawa M, Ezaki H, Sakamori R, Yakushijin T et al (2015) Solitary fibrous tumor of the liver from development to resection. Intern Med 54(7):765–770
Moser T, Nogueira TS, Neuville A, Riehm S, Averous G, Weber JC et al (2005) Delayed enhancement pattern in a localized fibrous tumor of the liver. Am J Roentgenol maggio 184(5):1578–1580
Xie GY, Zhu HB, Jin Y, Li BZ, Yu YQ, Li JT (2022) Solitary fibrous tumor of the liver: a case report and review of the literature. World J Clin Cases 10(20):7097–7104
Luo L, Wang T, Cheng M, Ge X, Song S, Zhu G et al (2023) Rare benign liver tumors that require differentiation from hepatocellular carcinoma: focus on diagnosis and treatment. J Cancer Res Clin Oncol luglio 149(7):2843–2854
Korkolis DP, Apostolaki K, Aggeli C, Plataniotis G, Gontikakis E, Volanaki D et al (2008) Solitary fibrous tumor of the liver expressing CD34 and vimentin: a case report. World J Gastroenterol WJG. 14(40):6261–4
Novais P, Robles-Medranda C, Pannain VL, Barbosa D, Biccas B, Fogaça H (2010) Solitary fibrous liver tumor: is surgical approach the best option? J Gastrointestin Liver Dis 19(1):81–4
Chen JJ, Ong SL, Richards C, Garcea G, Pollard C, Berry D et al (2008) Inaccuracy of fine-needle biopsy in the diagnosis of solitary fibrous tumour of the liver. Asian J Surg 31(4):195–8
Cresswell AB, Welsh FKS, Rees M (2009) A diagnostic paradigm for resectable liver lesions: to biopsy or not to biopsy? HPB novembre 11(7):533–540
Feng LH, Dong H, Zhu YY, Cong WM (2015) An update on primary hepatic solitary fibrous tumor: an examination of the clinical and pathological features of four case studies and a literature review. Pathol-Res Pract 211(12):911–7
Stacchiotti S, Libertini M, Negri T, Palassini E, Gronchi A, Fatigoni S et al (2013) Response to chemotherapy of solitary fibrous tumour: a retrospective study. Eur J Cancer 49(10):2376–83
Bagley JE, Paul DE, Halferty S, DiGiacinto D (2018) The use of contrast-enhanced ultrasonography for the characterisation of focal liver lesions. Sonography 5(3):120–134
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Meloni, M.F., Mariani, I., Galluzzi, P. et al. Contrast-enhanced ultrasound (CEUS): one step forward in the identification of “high risk” solitary fibrotic tumors of the liver. J Ultrasound (2024). https://doi.org/10.1007/s40477-024-00890-z
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DOI: https://doi.org/10.1007/s40477-024-00890-z