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Prevent surgical site infections in the elderly by taking an individualized approach to antibacterial selection

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Abstract

Advanced age is associated with an increased risk of surgical site infections (SSIs). Prevention and management of SSIs in the elderly is often difficult, with the use of antibacterial prophylaxis being further complicated by the increasing emergence of antibacterial-resistant pathogens. An individualized approach, therefore, is needed when selecting the most appropriate antibacterial agent for prophylaxis of SSIs in the elderly. As the pharmacodynamic and pharmacokinetic profiles of antibacterials may be altered in elderly patients, dosage adjustments may be needed to avoid overdosing and adverse events.

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The preparation of this review was not supported by any external funding.

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  1. Springer, Private Bag 65901, Mairangi Bay, Auckland, 0754, New Zealand

    Adis Medical Writers

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  1. Adis Medical Writers
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The article was adapted from Drugs & Aging 2017;34(7):489–98 [2] by employees of Adis/Springer, who are responsible for the article content and declare no conflicts of interest.

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Writers, A.M. Prevent surgical site infections in the elderly by taking an individualized approach to antibacterial selection. Drugs Ther Perspect 34, 169–172 (2018). https://doi.org/10.1007/s40267-017-0470-2

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