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Remarkable Role of Nanoscale Particles and Viscosity Variation in Blood Flow Through Overlapped Atherosclerotic Channel: A Useful Application in Drug Delivery

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Abstract

A theoretical model of blood flow through the curved atherosclerotic channel under the inspiration of different nanoparticles is presented in this investigation. The nonlinear coupled equations leading to the flow analysis are simplified by using atherosclerotic approximation. The exact closed-form solutions of temperature, velocity and hemodynamics impacts are evaluated by using appropriate boundary conditions. Shape effects of different nanoparticles are taken into account to attenuate the atherosclerotic lesion of curved channel. To discuss the hemodynamics impacts theoretically, experimental values of the solid nanoparticles and base fluid (blood) are considered in this analysis. Finally, possessions of some evolving physical parameters on arterial blood flow features are presented graphically and discussed in detail. A streamline configuration with trapped bolus phenomena is also presented to understand the blood flow pattern in the curved atherosclerotic channel.

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Authors and Affiliations

  1. Department of Mathematics, Faculty of Sciences, HITEC University, Taxila, Pakistan

    S. Ijaz & Z. Iqbal

  2. DBS&H, CEME, National University of Sciences and Technology, Islamabad, Pakistan

    H. Sadaf

Authors
  1. S. Ijaz
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  2. H. Sadaf
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  3. Z. Iqbal
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Correspondence to S. Ijaz.

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Ijaz, S., Sadaf, H. & Iqbal, Z. Remarkable Role of Nanoscale Particles and Viscosity Variation in Blood Flow Through Overlapped Atherosclerotic Channel: A Useful Application in Drug Delivery. Arab J Sci Eng 44, 6241–6252 (2019). https://doi.org/10.1007/s13369-019-03779-w

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  • DOI: https://doi.org/10.1007/s13369-019-03779-w

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