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Association of Loss of Occlusal Pairs of Teeth with Sarcopenia in a Chinese Population of Community-Dwelling Elderly

  • Original Research
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The journal of nutrition, health & aging

Abstract

Objectives

Tooth loss, which usually leads to malnutrition, is common in the elderly. However, limited information is available regarding its association with sarcopenia. This study aimed to investigate the relationship between loss of occlusal pairs of tooth and sarcopenia.

Design

A cross-sectional retrospective study was performed.

Setting

The elderly who participated in the National Basic Public Health Project in the Maigaoqiao Community Medical Center in Nanjing, Jiangsu Province, China.

Participants

A total of 2850 individuals aged ≥60 years were enrolled.

Measurements

Sarcopenia was defined according to the criteria proposed by the Asian Working Group for Sarcopenia. A trained dentist assessed oral health status and counted the number of present teeth. Logistic regression analyses were performed to evaluate the association between the loss of occlusal pairs and sarcopenia.

Results

The prevalence of sarcopenia was 7.1% (201/2850). Univariate logistic regression analysis showed that loss of occlusal pairs was associated with sarcopenia [anterior occlusal pairs (AOPs): odd ratio (OR) = 1.292, 95% confidence interval (CI) = 1.158–1.442; posterior occlusal pairs (POPs): OR = 1.147, 95% CI = 1.018–1.221]. Multivariate logistic regression analysis indicated that loss of POPs was still an independent risk for sarcopenia (OR = 1.108, 95% CI = 1.007–1.220) after adjustment for traditional confounders. Subgroup analysis showed that loss of POPs was more significantly linked to sarcopenia in those with advanced age (≥80years) (OR = 1.307, 95% CI = 1.116–1.532) and in females (OR = 1.165, 95%CI = 1.038–1.308). Compared to individuals with ≥5 occluding pairs of POPs, those with <5 occluding pairs of POPs had a higher incidence of sarcopenia.

Conclusions

Loss of POPs is associated with an increased risk of sarcopenia in the elderly in a Chinese population. Further research on the mechanism of the observed causal relationship is needed.

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Acknowledgments

The authors would like to thank the participating elderly and the clinicians who conducted the physical examination.

Funding

Funding Sources: This work was supported by grants from the National Key Research and Development Plan of China (No. 2020YFC2008505 to Xiang Lu), the National Natural Science Foundation of China (No. 81970218 to Xiang Lu and No. 81970217 to Wei Gao), the Six Talent Peaks Project of Jiangsu Province (No. WSN- 175 to Wei Gao), and Jiangsu Geriatrics Society (JGS2019ZXYY06 to Xiang Lu).

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Author notes

  1. These authors contributed equally to this work

Authors and Affiliations

  1. Department of Geriatrics, Sir Run Run Hospital, Nanjing Medical University, 211166, Nanjing, Jiangsu Province, China

    Y.-S. Lin, Q. Wang, H.-X. Sun, F. Xu, Y.-L. Bu, J.-W. Li, C. Zhao, X. Lu & Wei Gao

  2. Department of Geriatrics, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China

    C. Wu, H. He, G.-Q. Zou & M. Hong

  3. Jiangsu Province Center for Disease Control and Prevention, Nanjing, 210009, China

    Z.-K. Shen & Jin-Shui Xu

  4. Key Laboratory for Aging and Disease, Nanjing Medical University, Nanjing, China

    Y.-S. Lin, Q. Wang, H.-X. Sun, C. Wu, H. He, G.-Q. Zou, F. Xu, Y.-L. Bu, J.-W. Li, C. Zhao, M. Hong, X. Lu & Wei Gao

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  1. Y.-S. Lin
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  2. Q. Wang
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  3. Z.-K. Shen
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  5. C. Wu
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  11. C. Zhao
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  12. M. Hong
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  13. X. Lu
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  14. Jin-Shui Xu
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Corresponding authors

Correspondence to Jin-Shui Xu or Wei Gao.

Ethics declarations

Ethical standards: The protocol of present study confirmed by the Medical Ethics Committee at the Shoushtar Faculty of Medical Sciences, considering to the 2013 Helsinki Declaration guidelines with registration Number: (IR.SHOUSHTAR.REC.1399.027). All participants also signed a consent form.

Conflict of interest: The authors declare no conflicts of interest.

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Lin, YS., Wang, Q., Shen, ZK. et al. Association of Loss of Occlusal Pairs of Teeth with Sarcopenia in a Chinese Population of Community-Dwelling Elderly. J Nutr Health Aging 26, 439–444 (2022). https://doi.org/10.1007/s12603-022-1784-x

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