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In vitro biodegradability of Mg–2Gd–xZn alloys with different Zn contents and solution treatments

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Abstract

This study aims to investigate the addition of Zn on the corrosion property and cytocompatibility of Mg–2Gd–xZn (x = 0, 3, 4 and 5; wt%) alloys, which were prepared by gravity permanent mold casting and solution treatment, respectively. The results show that the intermetallic phases of these ternary alloys are mainly composed of Mg12GdZn and Mg3GdZn3. The content of secondary phases as well as the grain size is greatly dependent on the Zn addition. Compared to the binary Mg–2Gd alloy, the corrosion resistance of the most ternary alloys is significantly improved. Furthermore, the in vitro cell culture study demonstrates the potential cytocompatibility of the developed ternary alloys. It indicates that a series of Mg–2Gd–xZn (x = 0, 3, 4 and 5; wt%) with medically acceptable corrosion rate are developed and show great potential use as a new type of biodegradable implants.

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Acknowledgements

This work was financially supported by the National Natural Science Foundation of China (Nos. 31300808 and 31400815), the Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi (No. 201417) and the Natural Science Foundation of Shanxi Province (No. 2013021011-1).

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  1. Meng Zhang and Wei-Lin Deng have contributed equally to this work and should be considered co-first authors.

Authors and Affiliations

  1. College of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan, 030024, China

    Meng Zhang, Wei-Lin Deng, Xiao-Ning Yang, Yong-Kang Wang, Xiang-Yu Zhang, Rui-Qiang Hang & Xiao-Bo Huang

  2. Shanxi Key Laboratory of Advanced Magnesium-Based Materials, Taiyuan University of Technology, Taiyuan, 030024, China

    Kun-Kun Deng

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  1. Meng Zhang
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Correspondence to Xiao-Bo Huang.

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Zhang, M., Deng, WL., Yang, XN. et al. In vitro biodegradability of Mg–2Gd–xZn alloys with different Zn contents and solution treatments. Rare Met. 38, 620–628 (2019). https://doi.org/10.1007/s12598-019-01220-7

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