Abstract
Hydroxyapatite (HA) has generated a great deal of interest as a promising implant material. However, its poor mechanical properties induced by severe dissolution in biological milieu limit medical applications and lead to clinical failure. In this study, HA ceramics with 30P2O5-30CaO-40Na2O glass (1.0 wt.% and 2.5 wt.%) were prepared to improve the resistance of monophase HA. The monophase HA sintered body showed microstructural degradation due to grain boundary dissolution in buffered water. However, the dissolution-resistance of HA/glass composites was significantly improved and showed no apparent evidence of dissolution. This suggests that a less soluble glass phase should be placed at grain boundaries to protect HA from dissolution.
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Seo, D.S., Lee, J.K. Dissolution-resistance of glass-added hydroxyapatite composites. Met. Mater. Int. 15, 265–271 (2009). https://doi.org/10.1007/s12540-009-0265-7
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DOI: https://doi.org/10.1007/s12540-009-0265-7