Sponsorship, article processing charges, and the open access charge for this study were funded by AbbVie Inc. The authors would like to thank Donald Morisky, ScD, ScM, MSPH, UCLA Fielding School of Public Health, Department of Community Health Sciences, Los Angeles, California, USA, for permission to use the four-item Morisky Medication Adherence Scale (MMAS-4). Use of the ©MMAS is protected by US copyright laws. Permission for use is required. A license agreement is available from Professor Donald E. Morisky, Department of Community Health Sciences, UCLA Fielding School of Public Health, 650 Charles E. Young Drive South, Los Angeles, CA 90095-1772, email@example.com. The authors also thank Stefanie Kalus, PhD, GKM, Munich, Germany, for her statistical support, and Rita Tarzynski-Potempa, MD, AbbVie, for her scientific review. Furthermore, the authors would like to thank all investigators for their contribution to the success of the ALIGN study. Editorial assistance in the preparation of this manuscript was provided by Patrick Little, PhD, and Michael J. Theisen, PhD, of Complete Publication Solutions, LLC, North Wales, Pennsylvania, USA. Support for this assistance was funded by AbbVie Inc. AbbVie contributed to the study design, and was involved in the collection, analysis, and interpretation of the data, and in the writing, review, and approval of the publication. All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this manuscript, take responsibility for the integrity of the work as a whole, and have given final approval for the version to be published.
Pierre Michetti has received consulting fees from MSD, AbbVie, Calypso, Merck-Serono, Ferring, Vifor, UCB Pharma, Takeda, Nestlé Health Sciences, and Pfizer, lecture fees from MSD, AbbVie, Falk, AstraZeneca, Takeda, Ferring, Vifor, UCB Pharma, grants from MSD, UCB Pharma, and Takeda, and personal fees from AbbVie during the conduct of the study; John Weinman is a part-time employee of Atlantis Healthcare, who develop patient support programs for many pharmaceutical companies, and has received consulting and lecture fees from AbbVie, Boehringer Ingelheim, Ferring, Roche, and Sanofi; Ulrich Mrowietz has received speaker and advisory board honoraria from AbbVie, grants from AbbVie for educational projects, and other compensation from AbbVie for clinical trial research; Josef Smolen has received grants and personal fees from AbbVie, Lilly, MSD, Pfizer, and Roche and personal fees from Amgen, AstraZeneca, Astro, Celgene, GlaxoSmithKline, Janssen, MedImmune, Novartis, Samsung, and UCB; Laurent Peyrin-Biroulet has received consulting fees from Merck, AbbVie, Janssen, Genentech, Mitsubishi, Ferring, Norgine, Tillotts, Vifor, Therakos, Pharmacosmos, Pilège, BMS, UCB Pharma, Hospira, Celltrion, Takeda, Biogaran, Boehringer Ingelheim, Lilly, Pfizer, H.A.C. Pharma, and Index Pharmaceuticals, and lecture fees from Merck, AbbVie, Takeda, Janssen, Ferring, Norgine, Tillotts, Vifor, Therakos, Mitsubishi, and H.A.C. Pharma; Edouard Louis has received grants from AbbVie and MSD, personal fees from AbbVie, MSD, Ferring, Takeda, Celltrion, Mundipharma, Hospira, and Janssen, and non-financial support from AbbVie and MSD; Dieter Schremmer is an employee of the contract research organization GKM Gesellschaft für Therapieforschung mbH; Namita Tundia is an AbbVie employee and shareholder of AbbVie stock; Pascal Nurwakagari was an AbbVie employee and shareholder of AbbVie stock at the time of the study; Nicole Selenko-Gebauer is an AbbVie employee and shareholder of AbbVie stock.
Compliance with Ethics Guidelines
All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964, as revised in 2013. Informed consent was obtained from all patients for being included in the study. This study was approved by the local ethics committee of each participating country.
The datasets during and/or analyzed during the current study are available from the corresponding author on reasonable request.
This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.