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Know when and how to die: gaining insights into the molecular regulation of leaf senescence

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Abstract

Senescence is the ultimate phase in the life cycle of leaves which is crucial for recycling of nutrients to maintain plant fitness and reproductive success. The earliest visible manifestation of leaf senescence is their yellowing, which usually commences with the breakdown of chlorophyll. The degradation process involves a gradual and highly coordinated disassembly of macromolecules resulting in the accumulation of nutrients, which are subsequently mobilized from the senescing leaves to the developing organs. Leaf senescence progresses under overly tight genetic and molecular control involving a well-orchestrated and intricate network of regulators that coordinate spatio-temporally with the influence of both internal and external cues. Owing to the advancements in omics technologies, the availability of mutant resources, scalability of molecular analyses methodologies and the advanced capacity to integrate multidimensional data, our understanding of the genetic and molecular basis of leaf ageing has greatly expanded. The review provides a compilation of the multitier regulation of senescence process and the interrelation between the environment and the terminal phase of leaf development. The knowledge gained would benefit in devising the strategies for manipulation of leaf senescence process to improve crop quality and productivity.

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Acknowledgements

Research fundings from PURSE (Promotion of University Research and Scientific Excellence) and CRG (Core Research Grant) grants of Department of Science and Technology (DST), Government of India; DU-IoE (Delhi University-Institute of Eminence, IoE/FRP/LS/2020/27), Delhi, India; UGC (University Grants Commission, 41-512/2021(SR)) and DBT (Department of Biotechnology), Government of India are acknowledged.

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  1. Department of Plant Molecular Biology, University of Delhi South Campus, Benito Juarez Road, New Delhi, 110021, India

    Jyothish Madambikattil Sasi, Shitij Gupta, Apurva Singh, Alice Kujur & Surekha Katiyar-Agarwal

  2. Department of Botany, University of Delhi North Campus, Delhi, 110007, India

    Manu Agarwal

  3. USDA-ARS Plant Genetics Research Unit, The Donald Danforth Plant Science Center, St. Louis, MO, 63132, USA

    Alice Kujur

  4. Centre of Excellence in Genomics and Systems Biology (CEGSB), International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), Patancheru, Hyderabad, Telangana, 502324, India

    Alice Kujur

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Sasi, J.M., Gupta, S., Singh, A. et al. Know when and how to die: gaining insights into the molecular regulation of leaf senescence. Physiol Mol Biol Plants 28, 1515–1534 (2022). https://doi.org/10.1007/s12298-022-01224-1

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