Nano Research

, Volume 3, Issue 7, pp 481–489

Biosynthesis of biocompatible cadmium telluride quantum dots using yeast cells

Open Access
Research Article

DOI: 10.1007/s12274-010-0008-6

Cite this article as:
Bao, H., Hao, N., Yang, Y. et al. Nano Res. (2010) 3: 481. doi:10.1007/s12274-010-0008-6


We demonstrate a simple and efficient biosynthesis method to prepare easily harvested biocompatible cadmium telluride (CdTe) quantum dots (QDs) with tunable fluorescence emission using yeast cells. Ultraviolet-visible (UV-vis) spectroscopy, photoluminescence (PL) spectroscopy, X-ray diffraction (XRD), and transmission electron microscopy (TEM) confirm that the CdTe QDs are formed via an extracellular growth and subsequent endocytosis pathway and have size-tunable optical properties with fluorescence emission from 490 to 560 nm and a cubic zinc blende structure with good crystallinity. In particular, the CdTe QDs with uniform size (2-3.6 nm) are protein-capped, which makes them highly soluble in water, and in situ bio-imaging in yeast cells indicates that the biosynthesized QDs have good biocompatibility. This work provides an economic and environmentally friendly approach to synthesize highly fluorescent biocompatible CdTe QDs for bio-imaging and bio-labeling applications.


Cadmium telluride (CdTe) quantum dots biosynthesis biocompatible in situ bio-imaging 

Supplementary material

12274_2010_8_MOESM1_ESM.pdf (677 kb)
Supplementary material, approximately 340 KB.

Copyright information

© Tsinghua University Press and Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Haifeng Bao
    • 1
  • Na Hao
    • 1
  • Yunxia Yang
    • 1
  • Dongyuan Zhao
    • 1
  1. 1.Department of Chemical EngineeringMonash UniversityClaytonAustralia

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