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Editierung induzierter pluripotenter Stammzellen mittels CRISPR/Cas9

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Abstract

The rapid development of the new genome editing technique CRISPR/ Cas9 enables easy and efficient modifications to the human genome. In combination with autologous cell transplants derived from induced pluripotent stem cells, a versatile platform for individualised cell therapies is entering pre-clinical evaluation.

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Authors and Affiliations

  1. Translationale Hepatologie und Stammzellbiologie, Abteilung für Gastroenterologie, Hepatologie und Endokrinologie Medizinische Hochschule Hannover, Carl-Neuberg-Straβe 1, D-30625, Hannover, Germany

    Susan Sgodda & Tobias Cantz

Authors
  1. Susan Sgodda
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  2. Tobias Cantz
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Additional information

Susan Sgodda Jahrgang 1977. Biologiestudium an der Universität Halle-Wittenberg mit dem Schwerpunkt Entwicklungsbiologie; dort 2004–2005 wissenschaftliche Mitarbeiterin am Institut für Physiologische Chemie und 2005–2009 wissenschaftliche Mitarbeiterin am Institut für Biochemie. Seit 2011 wissenschaftliche Mitarbeiterin in verschiedenen interdisziplinären BMBF-Projekten an der Medizinischen Hochschule Hannover.

Tobias Cantz Jahrgang 1972. Medizinstudium an der Universität Heidelberg. 2000 Promotion in der Abteilung Tumorbiochemie bei Prof. Dr. D. Keppler am DKFZ Heidelberg. 2000–2004 Assistenzarzt an der Klinik für Gastroenterologie, Hepatologie und Endokrinologie bei Prof. Dr. M. Manns, Medizinische Hochschule Hannover. 2004–2008 Postdoc am Max- Planck-Institut für molekulare Biomedizin Münster bei Prof. Dr. H. Schöler. Seit 2008 Gruppenleiter im Exzellenzcluster REBIRTH und seit 2014 Professor für Translationale Hepatologie und Stammzellbiologie an der Medizinischen Hochschule Hannover.

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Sgodda, S., Cantz, T. Editierung induzierter pluripotenter Stammzellen mittels CRISPR/Cas9. Biospektrum 24, 707–708 (2018). https://doi.org/10.1007/s12268-018-0984-8

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  • DOI: https://doi.org/10.1007/s12268-018-0984-8

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