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Laparoscopic Right Hepatectomy is as Safe and Feasible as Open Procedure in the Treatment of Liver Tumors: Meta-analysis

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Indian Journal of Surgery Aims and scope Submit manuscript

A Letter to Editor to this article was published on 21 November 2021

Abstract

The purpose of this study was to compare the clinical effect of laparoscopic right hepatectomy (LRH) and open right hepatectomy (ORH) in the treatment of liver tumor. Patients and Methods We systematically searched PubMed, web of science, EMBASE, clinicaltrials.gov, and Cochrane Central Register for studies (study published August 1947 to December 2019). In this study, the perioperative data of laparoscopic right hepatectomy and open right hepatectomy were analyzed. Our meta-analysis included 7 studies involving 633 patients who underwent two types of surgery, laparoscopic right hepatectomy and open right hepatectomy. This study showed that compared with open right hepatectomy, there was no significant difference in operative time (weighted mean difference (WMD): 35.28, 95% confidence interval (CI): − 9.04–79.60, P = 0.12), but the result of laparoscopic right hepatectomy’s R0 resections (odd ratio (OR): 2.34, 95% confidence interval (CI): 0.60–9.11, P = 0.22), transfusion (odd ratio (OR): 0.64, 95% confidence interval (CI): 0.34–1.20, P = 0.17), mortality (odd ratio (OR): 0.44, 95% confidence interval (CI): 0.14–1.45, P = 0.18) was similar to that of open right hepatectomy. Laparoscopic right hepatectomy resulted in shorter hospital stay (weighted mean difference (WMD): − 4.75, 95% confidence interval (CI): − 5.96–3.55, P<0.00001) and less estimated blood loss (EBL) (weighted mean difference (WMD): − 161.97, 95% confidence interval (CI): − 257.47–66.46, P = 0.0009). The clinical effect of laparoscopic right hepatectomy in the treatment of liver tumor was similar to that of open right hepatectomy, which was safe, feasible, and has a good prognosis.

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Data Availability

All data generated or analyzed during this study are included in this published article.

Abbreviations

LRH:

laparoscopic right hepatectomy

ORH:

open right hepatectomy

EBL:

estimated blood loss

LLR:

laparoscopic liver resection

HCC:

hepatocellular cancer

ICG:

indocyanine green

WMD:

weighted mean difference

SMD:

standard mean difference

OR:

odd ratio

CI:

confidence interval

OS:

overall survival

DFS:

disease-free survival

TACE:

transarterial chemoembolization

PVE:

portal venous embolization

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Authors and Affiliations

  1. Department of General Surgery, Hangzhou Normal University Affiliated Hospital, Hangzhou, People’s Republic of China

    Quan-li Zhu & Guo Liang Li

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  1. Quan-li Zhu
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QLZ designed the study. QLZ and GLL searched the articles and analyzed the data. QLZ wrote the manuscript. All authors read and approved the final manuscript.

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Correspondence to Quan-li Zhu.

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Zhu, Ql., Li, G.L. Laparoscopic Right Hepatectomy is as Safe and Feasible as Open Procedure in the Treatment of Liver Tumors: Meta-analysis. Indian J Surg 84 (Suppl 2), 357–364 (2022). https://doi.org/10.1007/s12262-021-02824-z

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