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Updates in biological therapies for knee injuries: tendons

  • Knee: Stem Cells (M Ferretti, Section Editor)
  • Published:
Current Reviews in Musculoskeletal Medicine Aims and scope Submit manuscript

Abstract

Tendons are subjected to tendinopathies caused by inflammation, degeneration, and weakening of the tendon, due to overuse and trauma, which may eventually lead to tendon rupture. Recently, there has been increasing interest in biological approaches to augment tissue healing. Tendon healing occurs through a dynamic process with inflammation, cellular proliferation, and tissue remodeling. In this review article, we discuss the more frequently proposed biological therapies for tendon injuries as platelet-rich plasma, mesenchymal stem cells, extracorporeal shockwave, and scaffolds.

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Conflict of Interest

Marco Kawamura Demange and Adriano Marques de Almeida declare that they have no conflict of interest. Scott A. Rodeo is a consultant for Rotation Medical and has stock with Cayenne Medical.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. Knee Surgery Division, Hospital das Clínicas, Orthopedic Surgery, Faculty of Medicine, University of São Paulo - Brazil, São Paulo, Brazil

    Marco Kawamura Demange

  2. Rua Ouvidio Pires de Campos, 333, São Paulo, Brazil, ZIP 05403-010

    Marco Kawamura Demange

  3. Hospital das Clínicas, University of São Paulo - Brazil, São Paulo, Brazil

    Adriano Marques de Almeida

  4. Sports Medicine and Shoulder Service Orthopaedic Surgery, The Hospital for Special Surgery, Weill Medical College of Cornell, USA, New York, NY, USA

    Scott A. Rodeo

  5. New York Giants Football, USA, New York, NY, USA

    Scott A. Rodeo

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  1. Marco Kawamura Demange
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  2. Adriano Marques de Almeida
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  3. Scott A. Rodeo
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Correspondence to Marco Kawamura Demange.

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Demange, M.K., de Almeida, A.M. & Rodeo, S.A. Updates in biological therapies for knee injuries: tendons. Curr Rev Musculoskelet Med 7, 239–246 (2014). https://doi.org/10.1007/s12178-014-9230-2

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