Abstract
Combined with ultrahigh-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), a method for simultaneous determination of 15 sulfonamides in livestock and poultry manure was established and further optimizes and improves the pre-treatment conditions. In this study, Fe3O4-multi-walled carbon nanotubes (MWCNTs) were used as the purification material, and achieved solid-liquid separation by an external magnet, which was faster than the traditional centrifugation process. The results showed that the recoveries of sulfonamides were from 89 to 119% and had relative standard deviations (RSDs) of less than 10%. The limit of detection (LOD) of the method was reached 0.5 to 1.0 μg/kg, and the limit of quantification (LOQ) was between 1.0 and 3.0 μg/kg. On the premise that a satisfactory recoveries can be obtained, Fe3O4-MWCNTs can be effectively used at least 3 times. We can conclude that this method has certain applicability and reliability in the analysis and detection of sulfonamides in livestock and poultry manure.
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This work was supported by the Shandong Key R & D Plan (Major Scientific and Technological Innovation Project) (2019JZZY020903), Shandong Academy of Agricultural Sciences Agricultural Science, Technology Innovation Engineering Industry Major Technological Innovation (CXGC2016B17), and the National Natural Science Foundation of China (Grant No. 41907030).
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Yan Zheng declares that he/she has no conflict of interest. Lixia Fan declares that he/she has no conflict of interest. Yanjie Dong declares that he/she has no conflict of interest. Dapeng Li declares that he/she has no conflict of interest. Lingjun Zhao declares that he/she has no conflict of interest. Xuexia Yuan declares that he/she has no conflict of interest. Lei Wang declares that he/she has no conflict of interest. Shancang Zhao declares that he/she has no conflict of interest.
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Zheng, Y., Fan, L., Dong, Y. et al. Determination of Sulfonamide Residues in Livestock and Poultry Manure Using Carbon Nanotube Extraction Combined with UPLC-MS/MS. Food Anal. Methods 14, 641–652 (2021). https://doi.org/10.1007/s12161-020-01910-4
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DOI: https://doi.org/10.1007/s12161-020-01910-4