Abstract
Introduction
Our objective is to emphasize the importance of recognizing and rapidly treating spontaneous spinal epidural hematoma (SSEH). SSEH is a pathologic entity traditionally thought to be exceptionally rare but which, in the era of MR imaging, is becoming increasingly prevalent, and which if treated with sufficient rapidity can be completely curable.
Clinical Presentation
Our particular case presented with clumsiness, neck pain with radiation to both arms, and bilateral arm weakness. According to the literature surveyed, most patients present with severe back and/or neck pain, often with a radicular component, followed by motor and/or sensory deficits.
Intervention/Technique
C5-6 decompressive hemilaminectomy with evacuation of hematoma.
Conclusion
As evidenced in the literature, outcome depends on time to operation and prognosis is impacted by age and preoperative deficit. Because of the high risk of poor outcome without treatment, SSEH should always be a diagnostic consideration in patients whose presentation is even slightly suggestive. Rapid, appropriate treatment of these patients can often lead to complete recovery of function, whereas any delay in appropriate treatment can be catastrophic.
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References
Jackson R. A case of spinal apoplexy. Lancet. 1869;2:5–6.
Bain N. A case of haematorrachis. Br Med J. 1897;2:455.
Groen R. Non-operative treatment of spontaneous spinal epidural hematomas: a review of the literature and a comparison with operative cases. Acta Neurochir (Wien). 2004;146(2):103–10.
Oldenkott P, Preger R, Todorov S. Spinale epidurale Hämatome und Antikoagulantienbehandlung. Med Welt. 1981;32:46–9.
Alexiadou-Rudolf C, Ernestus RI, Nanassis K, Lanfermann H, Klug N. Acute nontraumatic spinal epidural hematomas. An important differential diagnosis in spinal emergencies. Spine. 1998;23(16):1810–3.
Avrahami T, Ram A. MR demonstration of spontaneous acute epidural hematoma of the thoracic spine. Neuroradiology. 1989;31:89–92.
Bernsen PL, Haan J, Vielvoye GJ, Peerlinck KM. Spinal epidural hematoma visualized by MRI. Neuroradiology. 1988;30:280.
Rothfus WE, Chedid MK, Deeb ZL, Abla AA, Maroon JC, Sherman RL. MR imaging in the diagnosis of spontaneous spinal epidural hematomas. J Comput Assist Tomogr. 1987;11(5):851–4.
Jamjoom ZA. Acute spontaneous spinal epidural hematoma: the influence of magnetic resonance imaging on diagnosis and treatment. Surg Neurol. 1996;46(4):345–9.
Beatty W. Spontaneous cervical epidural hematoma. J Neurosurg. 1984;61:143–8.
Holtas S, Heiling M, Lönntoft M. Spontaneous spinal epidural hematoma: findings at MR imaging and clinical correlation. Radiology. 1996;199(2):409–13.
Kreppel D, Antoniadis G, Seeling W. Spinal hematoma: a literature survey with meta-analysis of 613 patients. Neurosurg Rev. 2003;26:1–49.
Liao CC, Lee ST, Hsu WC, Chen LR, Lui TN, Lee SC. Experience in the surgical management of spontaneous spinal epidural hematoma. J Neurosurg. 2004;100(1 Suppl Spine):38–45.
Groen RJ, van Alphen HA. Operative treatment of spontaneous spinal epidural hematomas: a study of the factors determining postoperative outcome. Neurosurgery. 1997;39:494–508.
Awada A, Russell N, al Fayez N, Naufal R, al Kohlani H. Spontaneous cervical epidural hematoma: case report. Spinal Cord. 1998;36:71–2.
Forlodou P. Les Veines Épidurales Rachidiennes: Conceptions Anatomiques, Physiologiques et Radiologiques Actuelles: Nancy, Thèse Médecine; 1982.
Marmey G, Doyon D, David P. Diagnostic IRM: D’un hématome epidural cervical. J Radiol. 1990;71(10):549–53.
Locke GE, Giorgio AJ, Biggers SL Jr, Johnson AP, Salem F. Acute spinal epidural hematoma secondary to aspirin-induced prolonged bleeding. Surg Neurol. 1976;5:293–6.
Zuccarello M, Scanarini M, D’Avella D, Andrioli GC, Gerosa M. Spontaneous spinal extradural hematoma during anticoagulant therapy. Surg Neurol. 1980;14:411.
Silber SH. Complete nonsurgical resolution of a spontaneous spinal epidural hematoma. Am J Emerg Med. 1996;14:391–3.
Harik SI, Raichle ME, Reis DJ. Spontaneously remitting spinal epidural hematoma in a patient on anticoagulants. N Engl J Med. 1971;284:1355–7.
Foo D, Rossier AB. Preoperative neurological status in predicting surgical outcome of spinal epidural hematomas. Surg Neurol. 1981;15:389–401.
Brawn LA, Bergval UE, Davies-Jones GA. Spontaneous spinal epidural haematoma with spontaneous resolution. Postgrad Med J. 1986;62:885–7.
Küker W, Thiex R, Friese S, Freudenstein D, Reinges MH, Ernemann U, Kringes T, Skalej M. Spinal subdural and epidural haematomas: diagnostic and therapeutic aspects in acute and subacute cases. Acta Neurochir (Wien). 2000;142:777–85.
Spengos K, Tsivgoulis G, Zakopoulos N. Could high blood pressure be the cause of acute spontaneous spinal epidural hematoma? Eur J Emerg Med. 2007;14:59.
Bruyn GW, Bosma NJ. Handbook of clinical neurology. Amsterdam: North Holland Publishing; 1976.
Lawton MT, Porter RW, Heiserman JE, Jacobowitz R, Sonntag VK, Dickman CA. Surgical management of spinal epidural hematoma: relationship between surgical timing and neurological outcome. J Neurosurg. 1995;83:1–7.
Shin JJ, Kuh SU, Cho YE. Surgical management of spontaneous spinal epidural hematoma. Eur Spine J. 2006;15:998–1004.
Rohde V, Küker W, Reinges MH, Gilsbach JM. Microsurgical treatment of spontaneous and non-spontaneous spinal epidural hematomas: neurological outcome in relation to aetiology. Acta Neurochir (Wien). 2000;142:787–92.
Cooper DW. Spontaneous spinal epidural hematoma. J Neurosurg 1967;26:343–5.
McQuarrie IG. Recovery from paraplegia caused by spontaneous spinal epidural hematoma. Neurology. 1978;28:224–8.
Hirabayashi K, Miyakawa J, Satomi K, Maruyama T, Wakano K. Operative results and postoperative progression of ossification among patients with ossification of cervical posterior longitudinal ligament. Spine 1981;6(4):354–65.
Little CP, Patel N, Nagaria J, Kumar R, Nanra J, Bolger CM. Use of topically applied rt-PA in the evacuation of extensive acute spinal subdural haematoma. Eur Spine J. 2004;13:380–3.
Santiago P, Fessler RG. Minimally invasive surgery for the management of cervical spondylosis. Neurosurgery. 2007;60(1 Suppl 1):S160–5.
Rosen DS, O’Toole JE, Eichholz KM, Hrubes M, Huo D, Sandhu FA, Fessler RG. Minimally invasive lumbar spinal decompression in the elderly: outcomes of 50 patients aged 75 years and older. Neurosurgery. 2007;60(3):503–9.
Acknowledgments
The authors are grateful for the editorial assistance rendered by Ms. Jessica Kazmier. The authors have no financial interests to disclose.
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Thiele, R.H., Hage, Z.A., Surdell, D.L. et al. Spontaneous Spinal Epidural Hematoma of Unknown Etiology: Case Report and Literature Review. Neurocrit Care 9, 242–246 (2008). https://doi.org/10.1007/s12028-008-9083-x
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DOI: https://doi.org/10.1007/s12028-008-9083-x