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The Functional Metabolism and Molecular Biology of Vitamin D Action

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Abstract

The evolution of our understanding of the biological impact of vitamin D is briefly reviewed, with a focus on the physiology and endocrinology of the vitamin D system. This chapter attempts to bring the molecular discoveries in vitamin D metabolism and mechanisms of action into focus on known physiology and endocrinology. The latest developments on metabolism of vitamin D, the enzymes involved, and the genes responsible are presented. The impact of the molecular discoveries on current views of the importance of vitamin D in public health is also presented.

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  1. Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI, 53706, USA

    Lori A. Plum & Hector F. DeLuca

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  1. Lori A. Plum
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Correspondence to Hector F. DeLuca.

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Plum, L.A., DeLuca, H.F. The Functional Metabolism and Molecular Biology of Vitamin D Action. Clinic Rev Bone Miner Metab 7, 20–41 (2009). https://doi.org/10.1007/s12018-009-9040-z

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