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Repeated botulinum toxin injection for idiopathic overactive bladder: Will chemodenervation become a long-term solution?

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Abstract

Botulinum toxin A (BTX-A) has emerged as a novel treatment option for idiopathic overactive bladder (OAB) refractory to antimuscarinic agents. The clinical needs of refractory OAB patients have been recently met by sacral neuromodulation and augmentation enterocystoplasty. Important features of BTX-A should include safety, efficacy, and ease of delivery during long-term repeated usage. This article reviews the role of repeated BTX-A injections in the treatment of idiopathic OAB.

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Authors and Affiliations

  1. Department of Urology, University of Miami Miller School of Medicine, 1611 NW 10th Avenue, Miami, FL, 33136, USA

    Angelo E. Gousse

Authors
  1. Darius J. Unwala
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  2. Paholo Barboglio
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  3. Angelo E. Gousse
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Correspondence to Angelo E. Gousse.

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Unwala, D.J., Barboglio, P. & Gousse, A.E. Repeated botulinum toxin injection for idiopathic overactive bladder: Will chemodenervation become a long-term solution?. Curr Urol Rep 8, 419–424 (2007). https://doi.org/10.1007/s11934-007-0041-5

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  • DOI: https://doi.org/10.1007/s11934-007-0041-5

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