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Genetics of type 2 diabetes

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Abstract

After several years of uncertain progress, the stage is now set for a transformation in understanding the genetic landscape of type 2 diabetes. Advances in genome informatics, genotyping technology, and statistical methodology, allied to availability of large-scale clinical material, are having a salutary effect on susceptibility gene discovery. The advent of genuinely genome-wide association scans and the prospects for combining genetics with high-throughput genomics are additional sources of optimism for the future.

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Authors and Affiliations

  1. Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital Campus, Old Road, OX3 7LJ, Oxford, UK

    Mark I. McCarthy MD, FRCP

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  1. Mark I. McCarthy MD, FRCP
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  2. Eleftheria Zeggini PhD
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Correspondence to Mark I. McCarthy MD, FRCP.

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McCarthy, M.I., Zeggini, E. Genetics of type 2 diabetes. Curr Diab Rep 6, 147–154 (2006). https://doi.org/10.1007/s11892-006-0026-7

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  • DOI: https://doi.org/10.1007/s11892-006-0026-7

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