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Comparative study of molecular dynamics, diffusion, and permeability for ligands in biomembranes of different lipid composition

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Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology Aims and scope

Abstract

A comparative study of several model lipid bilayers of different composition, which included analysis of kinetic parameters of model lipid bilayers and permeability of bilayer membranes for small molecules, has been carried out. The conformity of results of numeric experiments to experimental data (structure of membrane lipid bilayers, lateral diffusion coefficients, and relative permeability of biomembranes for ligands) is discussed in the framework of a standard molecular dynamics protocol.

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Authors and Affiliations

  1. Lomonosov Moscow State University, Moscow, 119991, Russia

    K. V. Shaitan, M. Yu. Antonov, Ye. V. Tourleigh, O. V. Levtsova, K. B. Tereshkina & M. P. Kirpichnikov

  2. Ammosov Yakut State University, ul. Belinskogo 58, Yakutsk, 677000, Russia

    M. Yu. Antonov & I. N. Nikolaev

Authors
  1. K. V. Shaitan
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  2. M. Yu. Antonov
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  3. Ye. V. Tourleigh
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  4. O. V. Levtsova
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  5. K. B. Tereshkina
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  6. I. N. Nikolaev
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  7. M. P. Kirpichnikov
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Correspondence to K. V. Shaitan.

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Original Russian Text © K.V. Shaitan, M.Yu. Antonov, Ye.V. Tourleigh, O.V. Levtsova, K.B. Tereshkina, I.N. Nikolaev, M.P. Kirpichnikov, 2008, published in Biologicheskie Membrany, 2008, Vol. 25, No. 1, pp. 66–75.

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Shaitan, K.V., Antonov, M.Y., Tourleigh, Y.V. et al. Comparative study of molecular dynamics, diffusion, and permeability for ligands in biomembranes of different lipid composition. Biochem. Moscow Suppl. Ser. A 2, 73–81 (2008). https://doi.org/10.1007/s11827-008-1011-x

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  • DOI: https://doi.org/10.1007/s11827-008-1011-x

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