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Effect of duration of pneumoperitoneum on renal function in patients undergoing laparoscopic surgeries: a prospective observational study

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Abstract

This study aimed to assess the effect of pneumoperitoneum and, thereby, raised intra-abdominal pressure for different durations (≤ 1 h, 1–3 h and > 3 h) on renal function. One hundred and twenty adult patients were allocated to four groups—the Control Group A (N = 30; patients undergoing non-laparoscopic surgery) or Group B (N = 30; patients undergoing laparoscopic surgery with duration of pneumoperitoneum < 1 h) or Group C (N = 30; patients undergoing laparoscopic surgery with duration of pneumoperitoneum 1–3 h) or Group D (N = 30; patients undergoing laparoscopic surgery with duration of pneumoperitoneum > 3 h). The baseline, intraoperative (at the end of pneumoperitoneum/surgery), and postoperative (after 6 h) values of blood urea levels, creatinine clearance, and serum cystatin C were compared. The results showed that the raised IAP (10–12 mmHg) and varying durations of pneumoperitoneum (from less than 1 h to more than 3 h) did not significantly affect renal function measured in terms of change in serum cystatin levels from baseline to 6 h in postoperative period. The varying durations of pneumoperitoneum also did not significantly affect serum creatinine or blood urea levels in the postoperative period. CTRI registration: CTRI/2016/10/007334.

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Data availability statement is not applicable, as there is no additional data apart from the one mentioned in the manuscript.

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Acknowledgements

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Funding

The study was funded by PGIMER, Chandigarh (institute). No external funding received and no competing interests declared.

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Authors and Affiliations

  1. Department of Anaesthesia & Intensive Care, PGIMER (Postgraduate Institute of Medical Education and Research), Chandigarh, 160012, India

    Komal A. Gandhi, Neeru Sahni & Nidhi Bhatia

  2. Department of Biochemistry, PGIMER, Chandigarh, India

    Ravjit S. Jassal & Arnab Pal

Authors
  1. Komal A. Gandhi
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  2. Ravjit S. Jassal
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  3. Neeru Sahni
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  4. Nidhi Bhatia
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  5. Arnab Pal
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Contributions

All authors contributed to the study conception and design. Data collection was performed by all authors, data analysis was done by KAG, NS, NB, AP. The first draft was written by NS, and all authors gave their scientific input in previous versions of manuscript. All authors have read and approved the final manuscript.

Corresponding author

Correspondence to Neeru Sahni.

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The authors declare that there are no conflicts of interest.

Ethical approval

The study was approved by Institute Ethics Committee, PGIMER, Chandigarh, India (Ref No. NK/2235/Study/1553).

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Written informed consent was obtained from all participants for this study.

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Gandhi, K.A., Jassal, R.S., Sahni, N. et al. Effect of duration of pneumoperitoneum on renal function in patients undergoing laparoscopic surgeries: a prospective observational study. J Robotic Surg 17, 2253–2258 (2023). https://doi.org/10.1007/s11701-023-01644-5

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  • DOI: https://doi.org/10.1007/s11701-023-01644-5

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