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Effect of Biliopancreatic Limb Length on Weight Loss, Postoperative Complications, and Remission of Comorbidities in One Anastomosis Gastric Bypass: a Systematic Review and Meta-analysis

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Abstract

Aimed to evaluate the effects of biliopancreatic limb (BPL) length on weight loss, postoperative complications, and remission of comorbidities in OAGB.. An extensive search was conducted in PubMed, Scopus, EMBASE, and Google Scholar databases to find related OAGB articles. Both BPL length < 200 cm (by − 17.79, 95% CI − 19.23, − 16.34) and BPL length ≥ 200 cm (by − 14.93, 95% CI − 15.66, − 14.20) significantly decreased BMI. Regarding the effect of BPL length on comorbidities and postoperative complications, it was shown that BPL length < 200 cm is safer and more effective. Therefore, standardization of BPL length < 200 cm is suggested. Bypassing ≥ 200 cm of the small bowel does not ameliorate weight loss or resolve comorbidities significantly, and it is related to more frequent postoperative complications and nutritional deficiencies. Registration number in PROSPERO: PROSPERO 2021 CRD42021225499.

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Authors and Affiliations

  1. Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Erfan Tasdighi, Maryam Barzin, Farhad Hosseinpanah, Amir Ebadinejad, Nazanin Taraghikhah, Mahtab Niroomand, Majid Valizadeh & Behnaz Abiri

  2. Bariatric Unit, Sunderland Royal Hospital, Sunderland, UK

    Kamal K. Mahawar

  3. Nutrition and Metabolic Diseases Research Center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

    Anahita Mansoori

  4. Tehran Obesity Treatment Center, Department of Surgery, Faculty of Medicine, Shahed University, Tehran, Iran

    Alireza Khalaj

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  1. Erfan Tasdighi
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  2. Maryam Barzin
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Correspondence to Behnaz Abiri.

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Key Points

• According to the evidence, standardization of BPL length < 200 cm in OAGB is suggested.

• BPL length ≥ 200 is associated with lower weight loss or comorbidity resolution in comparison with BPL length < 200 in OAGB.

• BPL length ≥ 200 in OAGB is associated with more frequent postoperative complications and nutritional deficiencies.

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Tasdighi, E., Barzin, M., Mahawar, K.K. et al. Effect of Biliopancreatic Limb Length on Weight Loss, Postoperative Complications, and Remission of Comorbidities in One Anastomosis Gastric Bypass: a Systematic Review and Meta-analysis. OBES SURG 32, 892–903 (2022). https://doi.org/10.1007/s11695-021-05848-2

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