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Comparison of the Bile Reflux Frequency in One Anastomosis Gastric Bypass and Roux-en-Y Gastric Bypass: a Cohort Study

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Abstract

Introduction

One of the most acceptable procedures in bariatric surgery is laparoscopic gastric bypass. Laparoscopic Roux-en-Y gastric bypass (RYGB) is a common technique used in bariatric surgery. Recently, one anastomosis gastric bypass (OAGB) has been suggested as a simple, fast, and effective technique for obesity treatment. This study aims to compare the frequency of histologically proven bile reflux in OAGB and RYGB among patients with morbid obesity.

Methods

This prospective cohort study was performed from 2015 to 2017 in the Department of Bariatric Surgery of Isfahan University of Medical Sciences, Isfahan, Iran. Patients who had undergone RYGB or OAGB surgery were enrolled. Patients who had undergone revisional surgery were excluded. Data on demographics, symptoms, fasting blood sugar, lipid profile, endoscopic, and histologic findings (based on the Sydney bile reflux index) of bile reflux and postoperative complications were collected and compared for the two techniques.

Results

A total of 122 obese patients (22 males) who had undergone RYGB or OAGB surgery were included. The Sydney bile reflux index showed no statistically significant difference between RYGB and OAGB groups. Similarly, no statistically significant difference was found in the self-reported history of bile reflux–related symptoms, bile reflux markers in esophagogastroduodenoscopy, and postoperative complications between groups.

Conclusions

OAGB and RYGB appear to be equal with respect to postoperative complications, bile reflux frequency, bile reflux index, and the Sydney system score.

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Acknowledgements

We would like to express our very great appreciation to Dr. Shervin Badihian for his valuable comments and suggestions during several stages of this research.

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Authors and Affiliations

  1. Minimally Invasive Surgery Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

    Behrouz Keleidari, Mohsen Mahmoudieh, Amir Hosein Davarpanah Jazi, Hamid Melali & Farid Nasr Esfahani

  2. Department of Minimally Invasive Surgery, Al Zahra Hospital, Isfahan, Iran

    Behrouz Keleidari, Mohsen Mahmoudieh, Amir Hosein Davarpanah Jazi & Hamid Melali

  3. Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

    Farid Nasr Esfahani

  4. Department of Gastroenterology, Isfahan University of Medical Sciences, Isfahan, Iran

    Mohammad Minakari

  5. Department of Pathology, Isfahan University of Medical Sciences, Isfahan, Iran

    Mojgan Mokhtari

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  1. Behrouz Keleidari
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  2. Mohsen Mahmoudieh
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  3. Amir Hosein Davarpanah Jazi
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  5. Farid Nasr Esfahani
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Correspondence to Mohsen Mahmoudieh.

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This study was approved by the Ethical research committee of Isfahan University of Medical Sciences, and all participants provided written voluntary informed consent

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The authors declare that they have no conflict of interest.

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Keleidari, B., Mahmoudieh, M., Davarpanah Jazi, A.H. et al. Comparison of the Bile Reflux Frequency in One Anastomosis Gastric Bypass and Roux-en-Y Gastric Bypass: a Cohort Study. OBES SURG 29, 1721–1725 (2019). https://doi.org/10.1007/s11695-018-03683-6

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