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Development of an efficient electrochemical sensor based on MoS2 nanosheets and ionic liquid modified carbon paste electrode for determination of ascorbic acid in the presence of vitamin B6

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Abstract

This work modified the carbon paste electrode (CPE) with MoS2 nanosheets and ionic liquid (IL), creating a simple and effective sensing platform. In contrast to oxidation at the bare CPE, which occurred at 518 mV (6.2 μA), the electro-oxidation of ascorbic acid at the MoS2-modified ILCPE occurred at 320 mV (20 μA). The MoS2/ILCPE also improved the rate of electrochemical reaction. When the concentration of ascorbic acid increased between 1.0 and 1000.0 μM, the peak current increased according to the differential pulse voltammetry (DPV) technique. The proposed MoS2/ILCPE sensor revealed a low limit of detection (LOD) of 0.2 μM and good sensitivity of 0.1011 μA μM− 1 for a wide range of concentrations of ascorbic acid from 1.0 to 1000.0 μM. A well-defined and distinct oxidation peak of ascorbic acid and vitamin B6 were found at 330 mV and 720 mV, respectively, according to the results of the analysis of ascorbic acid when vitamin B6 is present. Finally, in real-sample matrices, the proposed sensor showed a reasonable recovery of the spiked ascorbic acid and vitamin B6 (ascorbic acid injection, ascorbic acid tablet, vitamin B6 tablet, and urine samples).

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  1. Department of Chemistry, Graduate University of Advanced Technology, Kerman, Iran

    Hadi Soltani-Nejad

  2. Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran

    Fariba Garkani Nejad & Hadi Beitollahi

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  1. Hadi Soltani-Nejad
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Soltani-Nejad, H., Nejad, F.G. & Beitollahi, H. Development of an efficient electrochemical sensor based on MoS2 nanosheets and ionic liquid modified carbon paste electrode for determination of ascorbic acid in the presence of vitamin B6. Food Measure 18, 1318–1327 (2024). https://doi.org/10.1007/s11694-023-02216-9

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