Skip to main content
SpringerLink
Log in

Influence of roasting degrees on the antioxidant and anti-angiogenic effects of Coffea liberica

  • Original Paper
  • Published:
Journal of Food Measurement and Characterization Aims and scope Submit manuscript

Abstract

Coffee consumption has been associated with many health benefits, that the naturally occurring phytochemicals in coffee are believed to have anti-cancer properties. Unfortunately, established phytochemicals study are scarce. Hence, the present study aimed to evaluate the antioxidant and anti-angiogenic activities of Coffea liberica as influenced by different roasting degrees. Green and roasted (light, medium, dark) Coffea liberica beans were extracted using soxhlet extraction and cold infusion. Preliminary screening showed that roasting did not affect the phytochemicals qualitatively. Light roasted coffee infusion extract had the highest total phenolic content (366.72 ± 1.54 µg/mL) and percentage scavenging; light roasted coffee soxhlet extract had the highest total flavonoid content (324.67 ± 1.19 µg/mL), and green beans soxhlet extract exhibited the highest anti-angiogenic activity with an average score of 1.33. In conclusion, these findings endorse further investigations to determine the active principles and their mode of actions for potential preventative therapies against angiogenesis-related diseases.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. I. Ismail, M.S. Anuar, R. Shamsudin, Pertanika J. Sci. Technol. 22(1), 65 (2014)

    Google Scholar 

  2. A.K.-C. Saw, W.-S. Yam, K.-C. Wong, C.-S. Lai, J. Essent. Oil-Bear. Plants 18(1), 64 (2015)

    Article  CAS  Google Scholar 

  3. S.O. Antwi, J.E. Eckel-Passow, N.D. Diehl, D.J. Serie, K.M. Custer, M.L. Arnold, K.J. Wu, J.C. Cheville, D.D. Thiel, B.C. Leibovich, A.S. Parker, Cancer Causes Control 28(8), 857 (2017)

    Article  Google Scholar 

  4. F. Bravi, C. Bosetti, A. Tavani, S. Gallus, C. La Vecchia, Clin. Gastroenterol. Hepatol. 11(11), 1413 (2013)

    Article  CAS  Google Scholar 

  5. R.B. Postuma, A.E. Lang, R.P. Munhoz, K. Charland, A. Pelletier, M. Moscovich, L. Filla, D. Zanatta, S.R. Romenets, R. Altman, R. Chuang, B. Shah, Neurology 79(7), 651 (2012)

    Article  CAS  Google Scholar 

  6. N.P. Paynter, H.-C. Yeh, S. Voutilainen, M.I. Schmidt, G. Heiss, A.R. Folsom, F.L. Brancati, W.H.L. Kao, Am. J. Epidemiol. 164(11), 1075 (2006)

    Article  Google Scholar 

  7. M.S. Butt, M.T. Sultan, Crit. Rev. Food Sci. Nutr. 51(4), 363 (2011)

    Article  CAS  Google Scholar 

  8. M.S. Alkaltham, A. Salamatullah, K. Hayat, J. Food Meas. Charact. 14, 1306 (2020)

    Article  Google Scholar 

  9. J.A. Vignoli, M.C. Viegas, D.G. Bassoli, M.T. Benassi, Food Res. Int. 61, 279 (2014)

    Article  CAS  Google Scholar 

  10. A. Bridoux, S.A. Mousa, M.-M. Samama, J. Mal. Vasc. 37(3), 132 (2012)

    Article  CAS  Google Scholar 

  11. J. Folkman, Semin. Oncol. 29(6), 15 (2002)

    Article  CAS  Google Scholar 

  12. R. Mathur, S.K. Gupta, N. Singh, S. Mathur, V. Kochupillai, T. Velpandian, J. Ethnopharmacol. 105(3), 336 (2006)

    Article  Google Scholar 

  13. N. Kohli, P. Sawadkar, S. Ho, V. Sharma, M. Snow, S. Powell, M.A. Woodruff, L. Hook, E. García-Gareta, J. Tissue Eng. (2020). https://doi.org/10.1177/2041731420901621

    Article  PubMed  PubMed Central  Google Scholar 

  14. Z.I. Stryker, M. Rajabi, P.J. Davis, S.A. Mousa, Biomedicines (2019). https://doi.org/10.3390/biomedicines7020037

    Article  PubMed  PubMed Central  Google Scholar 

  15. C. Kim, H.G. Yu, J. Sohn, Korean J Ophthalmol 24(3), 163 (2010)

    Article  Google Scholar 

  16. C. Cárdenas, A.R. Quesada, M.A. Medina, Plos ONE 6(8), e23407 (2011). https://doi.org/10.1371/journal.pone.0023407

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. H. Li, S. Jin, H. Son, J. Seo, G. Jeong, Anat. Cell Biol. 46(1), 57 (2013)

    Article  Google Scholar 

  18. C.H. Yeh, Y.F. Liao, C.Y. Chang, J.N. Tsai, Y.H. Wang, C.C. Cheng, C.C. Wen, Y.H. Chen, Drug Chem. Toxicol. 35(4), 361 (2012)

    Article  CAS  Google Scholar 

  19. World Health Organisations, WHO Monographs on Selected Medicinal Plants (WHO, Geneva, 2000), p. 277

    Google Scholar 

  20. M.K.A. Sobuj, M.A. Islam, M.A. Haque, M.M. Islam, M.J. Alam, S.M. Rafiquzzaman, J. Food Meas. Charact. 15, 1653 (2021)

    Article  Google Scholar 

  21. E.K. Seow, S.M. Yeap, A.M. Easa, T.C. Tan, J. Food Meas. Charact. 15, 1644 (2021)

    Article  Google Scholar 

  22. D.-O. Kim, W.J. Seung, C.Y. Lee, Food Chem. 81(3), 321 (2003)

    Article  CAS  Google Scholar 

  23. U.S.M. Rao, M. Abdurrazak, K.S. Mohd, Malaysian J. Anal. Sci. 20(5), 1181 (2016)

    Article  Google Scholar 

  24. M.S. Daneshzadeh, H. Abbaspour, L. Amjad, A.M. Nafchi, J. Food Meas. Charact. 14, 708 (2020)

    Article  Google Scholar 

  25. A. Siddiqua, K.B. Premakumari, R. Sultana, V. Savitha, Int. J. Chemtech Res. 2(1), 205 (2010)

    CAS  Google Scholar 

  26. L.-J. Seow, H.-K. Beh, A.M.S.A. Majid, V. Murugaiyah, N. Ismail, M.Z. Asmawi, J. Ethnopharmacol. 134(2), 221 (2011)

    Article  CAS  Google Scholar 

  27. T. Pilipczuk, B. Kusznierewicz, D. Zielińska, A. Bartoszek, J. Food Sci. Technol. 52(9), 5736 (2015)

    Article  CAS  Google Scholar 

  28. M. Moeenfard, G.L. Erny, A. Alves, J. Food Meas. Charact. 14, 1451 (2020)

    Article  Google Scholar 

  29. I. Hečimović, A. Belščak-Cvitanović, D. Horžić, D. Komes, Food Chem. 129(3), 991 (2011)

    Article  Google Scholar 

  30. N. Liang, D.D. Kitts, Molecules 19(11), 19180 (2014)

    Article  Google Scholar 

  31. A.W. Griffioen, G. Molema, Pharmacol. Rev. 52(2), 237 (2000)

    CAS  PubMed  Google Scholar 

  32. N.N. Azwanida, Medicinal Aromat. Plants 4, 3 (2015). https://doi.org/10.4172/2167-0412.1000196

    Article  Google Scholar 

  33. K. Gopalasatheeskumar, Mintage J. Pharm. Med. Sci. 7(1), 2320 (2018)

    Google Scholar 

  34. A. Farah, in Coffee: Emerging Health Effects and Disease Prevention. ed. by Y.F. Chu (Blackwell Publishing Ltd, Oxford, 2012), p. 21

    Chapter  Google Scholar 

Download references

Acknowledgements

The authors wish to thank the Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak especially the laboratory assistants for their excellent assistance in making this research a success. The research reported in this paper was supported by the short-term research grant (STRG) (Grant No. UniKL/CoRI/str18024) awarded by Universiti Kuala Lumpur, Malaysia.

Author information

Authors and Affiliations

  1. Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak, 30450, Ipoh, Malaysia

    Lay-Jing Seow & Syafiqah Shamlan

  2. Department of Food Science and Technology, Faculty of Applied Sciences, Universiti Teknologi MARA, 40450, Shah Alam, Selangor, Malaysia

    Eng-Keng Seow

Authors
  1. Lay-Jing Seow
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Syafiqah Shamlan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Eng-Keng Seow
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

L-JS conceived the idea, supervised the work, carried out the experiments and wrote the MS; SS carried out the experiments and wrote the MS; E-KS supervised the work, analysed the data and edited the manuscript.

Corresponding authors

Correspondence to Lay-Jing Seow or Eng-Keng Seow.

Ethics declarations

Conflict of interest

The authors declare that they do not have any conflict of interest.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Seow, LJ., Shamlan, S. & Seow, EK. Influence of roasting degrees on the antioxidant and anti-angiogenic effects of Coffea liberica. Food Measure 15, 4030–4036 (2021). https://doi.org/10.1007/s11694-021-00987-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11694-021-00987-7

Keywords

Search

Navigation