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In vitro study of the antioxidant, photoprotective, anti-tyrosinase, and anti-urease effects of methanolic extracts from leaves of six Moroccan Lamiaceae

Journal of Food Measurement and Characterization volume 15, pages 1785–1795 (2021)Cite this article

Abstract

Six Lamiaceae from Morocco were screened for their antioxidant, photoprotective, anti-tyrosinase, and anti-urease effects in the aim to assess their possible use as a source of bioactive compounds. The amounts of different phenolic compounds were also quantified using calorimetric methods. The highest total phenolic content was recorded with Lavandula pinnata (400.67 ± 3.39 μg GAE/mg), while he uppermost amounts of total flavonoids and condensed tannins were observed with Mentha pulegium (208.31 ± 12.18 µg QE/mg and 43.81 ± 4.07 µg CE/mg, respectively). The strongest antioxidant effect against the DPPH radical was exhibited by Salvia officinalis with an IC50 of 4.33 ± 0.41 µg/mL, which was similar to the value presented by the standard BHA (5.73 ± 0.41 µg/mL) and 5 times less than that obtained with BHT (22.32 ± 1.19 µg/mL). Salvia officinalis also showed remarkable scavenging activity of the radical ABTS with an IC50 of 4.75 ± 0.47 µg/mL, which was slightly higher than those recorded with BHA and BHT (1.81 ± 0.10 and 1.29 ± 0.30 µg/mL, respectively). All the plants gave high values of SPF ranged between 34.66 ± 0.28 and 39.07 ± 1.06. Salvia officinalis presented the best inhibitory effects against tyrosinase and urease with IC50 values of 20.43 ± 1.39 and 10.38 ± 0.10 µg/mL, respectively and was more powerful than kojic acid and thiourea used as standards for each assay, respectively. These results showed the variety of actions exerted by the plants studied, which make them potential candidates as a source of bioactive substances for various applications.

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Acknowledgments

We are grateful to the Biotechnology Research Center, Constantine, (Algeria) helping us bring the present work to light.

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Authors and Affiliations

  1. Laboratory of Agro-Alimentary and Health, Faculty of Science and Technology, Hassan 1St University of Settat, 26000, Settat, Morocco

    Soukaina El Aanachi, Said Rammali, Hinde Aassila & Khadija Dari

  2. Centre de Recherche en Biotechnologie, Ali Mendjeli Nouvelle Ville, P.B E73/UV No 03, Constantine, Algérie

    Lynda Gali & Chawki Bensouici

Authors
  1. Soukaina El Aanachi
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  2. Lynda Gali
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  3. Said Rammali
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Correspondence to Soukaina El Aanachi.

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El Aanachi, S., Gali, L., Rammali, S. et al. In vitro study of the antioxidant, photoprotective, anti-tyrosinase, and anti-urease effects of methanolic extracts from leaves of six Moroccan Lamiaceae. Food Measure 15, 1785–1795 (2021). https://doi.org/10.1007/s11694-020-00759-9

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  • DOI: https://doi.org/10.1007/s11694-020-00759-9

Keywords

  • Lamiaceae
  • Phenolic contents
  • Antioxidant activity
  • Sun protection factor
  • Tyrosinase
  • Ureas