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Remote effects in the ipsilateral thalamus and/or contralateral cerebellar hemisphere using FDG PET in patients with brain tumors

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Abstract

Purpose

To evaluate reduced metabolism in the ipsilateral thalamus (TH) and/or contralateral cerebellum (CE) according to tumor localization and cortical metabolism around the tumor in patients with brain tumors based on FDG uptake.

Methods

This study investigated 48 consecutive patients with solitary cerebral hemisphere parenchymal brain tumors who underwent PET/CT and MRI. Patients were divided into 4 groups (A: reduced uptake in ipsilateral TH and contralateral CE, B: reduced uptake in ipsilateral TH only, C: reduced uptake in contralateral CE only, and D: no reduced uptake in ipsilateral TH or contralateral CE). FDG uptake and MRI findings were compared among these groups.

Results

Of 48 patients, group A included 24 (50%), group B included 10 (21%), group C included 0, and group D included 14 (29%). No significant tendencies were observed between the groups regarding tumor localization. However, reduced cortical metabolism around the tumor was observed in 22 patients in group A, 7 patients in group B, and 1 patient in group D. All patients in group B showed reduced metabolism from around the tumor up to the ipsilateral TH.

Conclusion

Reduced FDG uptake in ipsilateral TH and contralateral CE usually occur simultaneously in patients with solitary brain tumors.

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Authors and Affiliations

  1. Department of Radiology, Kochi Medical School, Kochi University, Kohasu, Okocho, Nankoku, Kochi, 783-8505, Japan

    Hitomi Iwasa, Yoriko Murata, Miki Nishimori, Kana Miyatake, Michiko Tadokoro & Takuji Yamagami

  2. Department of Radiology, Health care system JINSEI-KAI Hosogi Hospital, Daizencho, Kochi, Kochi, 780-0926, Japan

    Shino Kohsaki

  3. Department of Radiology, Kobe University Hospital, Kusunokicho Chuoku, Kobe, Hyogo, 650-0017, Japan

    Munenobu Nogami

  4. Department of Neurosurgery, Kochi Medical School, Kochi University, Kohasu, Okocho, Nankoku, Kochi, 783-8505, Japan

    Yusuke Ueba & Tetsuya Ueba

Authors
  1. Hitomi Iwasa
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  2. Yoriko Murata
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  3. Miki Nishimori
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  4. Kana Miyatake
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  5. Michiko Tadokoro
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  6. Shino Kohsaki
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  7. Munenobu Nogami
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  8. Yusuke Ueba
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  9. Tetsuya Ueba
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  10. Takuji Yamagami
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Corresponding author

Correspondence to Hitomi Iwasa.

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Iwasa, H., Murata, Y., Nishimori, M. et al. Remote effects in the ipsilateral thalamus and/or contralateral cerebellar hemisphere using FDG PET in patients with brain tumors. Jpn J Radiol 36, 303–311 (2018). https://doi.org/10.1007/s11604-018-0721-8

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  • DOI: https://doi.org/10.1007/s11604-018-0721-8

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