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Clinical features of hepatocellular carcinoma supplied by the left internal mammary artery

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Abstract

Purpose

To evaluate the clinical features of hepatocellular carcinoma (HCC) supplied by the left internal mammary artery (LIMA).

Materials and methods

This cohort included 12 HCCs of 12 patients supplied by the LIMA. The clinical features of these tumors were analyzed.

Results

The tumor diameters were 4.2 ± 4.4 cm (mean ± SD) located at the surface of segments 4 (n = 6), 3 (n = 3), 2 (n = 2), and 4–8 (n = 1), respectively. The tumor was supplied by the phrenic branch (n = 8) or musclophrenic artery (n = 4) entirely (n = 7) or partially (n = 5). Two patients with large tumors 10 and 16 cm in diameter, respectively, received no previous treatment. Ten patients had previously undergone 5.8 ± 3.7 TACE sessions including through extrahepatic collaterals. Selective TACE could not be completed in one. No TACE-related complications developed. Of 11 embolized tumors, six did not recur at 8.8 ± 4.6 months and five recurred 4.4 ± 2.6 months later.

Conclusion

The clinical features of HCC supplied by the LIMA can be divided into two categories, untreated large tumors and small tumors receiving multiple TACE sessions at the subcapsular area of the left hepatic lobe.

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References

  1. Kim HC, Chung JW, Lee W, Jae HJ, Park JH. Recognizing extrahepatic collateral vessels that supply hepatocellular carcinoma to avoid complications of transcatheter arterial chemoembolization. Radiographics. 2005;25:S25–39.

    Article  PubMed  Google Scholar 

  2. Miyayama S, Matsui O, Taki K, Minami T, Ryu Y, Ito C, et al. Extrahepatic blood supply to hepatocellular carcinoma: angiographic demonstration and transcatheter arterial chemoembolization. Cardiovasc Interv Radiol. 2006;29:39–48.

    Article  Google Scholar 

  3. Kim JH, Chung JW, Han JK, Park JH, Choi BI, Han MH. Transcatheter arterial embolization of the internal mammary artery in hepatocellular carcinoma. J Vasc Interv Radiol. 1995;6:71–7.

    Article  PubMed  CAS  Google Scholar 

  4. Nakai M, Sato M, Kawai N, Minamiguchi H, Masuda M, Tanihata H, et al. Hepatocellular carcinoma: involvement of the internal mammary artery. Radiology. 2001;219:147–52.

    PubMed  CAS  Google Scholar 

  5. Kim HC, Chung JW, Choi SH, Jae HJ, Lee W, Park JH. Internal mammary arteries supplying hepatocellular carcinoma: vascular anatomy at digital subtraction angiography in 97 patients. Radiology. 2007;242:925–32.

    Article  PubMed  Google Scholar 

  6. Kim HC, Chung JW, Choi SH, Yoon JH, Lee HS, Jae HJ, et al. Hepatocellular carcinoma with internal mammary artery supply: feasibility and efficacy of transarterial chemoembolization and factors affecting patient prognosis. J Vasc Interv Radiol. 2007;18:611–20.

    Article  PubMed  Google Scholar 

  7. Kim HC, Chung JW, Jae HJ, Jeon UB, Son KR, Park JH. Hepatocellular carcinoma: prediction of blood supply from an internal mammary artery with multi-detector row CT. J Vasc Interv Radiol. 2008;19:1419–26.

    Article  PubMed  Google Scholar 

  8. Kajiwara K, Kakizawa H, Takeuchi N, Toyota N, Hieda M, Ishikawa M, et al. Cutaneous complications after transcatheter arterial treatment for hepatocellular carcinoma via the internal mammary artery: how to avoid this complication. Jpn J Radiol. 2011;29:307–15.

    Article  PubMed  Google Scholar 

  9. Park SI, Lee DY, Won JY, Lee JT. Extrahepatic collateral supply of hepatocellular carcinoma by the intercostal arteries. J Vasc Interv Radiol. 2003;14:461–8.

    Article  PubMed  Google Scholar 

  10. Miyayama S, Yamashiro M, Okuda M, Aburano H, Shigenari N, Morinaga K, et al. Anastomosis between the hepatic artery and the extrahepatic collateral or between extrahepatic collaterals: observation on angiography. J Med Imaging Radiat Oncol. 2009;53:271–82.

    Article  PubMed  CAS  Google Scholar 

  11. Miyayama S, Yamashiro M, Okuda M, Yoshie Y, Nakashima Y, Ikeno H, et al. The march of extrahepatic collaterals: analysis of blood supply to hepatocellular carcinoma located in the bare area of the liver after chemoembolization. Cardiovasc Interv Radiol. 2010;33:513–22.

    Article  Google Scholar 

  12. Ibukuro K, Tsukiyama T, Mori K, Inoue Y. Hepatic falciform ligament artery: angiographic anatomy and clinical importance. Surg Radiol Anat. 1998;20:367–71.

    Article  PubMed  CAS  Google Scholar 

  13. Arora R, Soulen MC, Haskal ZJ. Cutaneous complications of hepatic chemoembolization via extrahepatic collaterals. J Vasc Interv Radiol. 1999;10:1351–6.

    Article  PubMed  CAS  Google Scholar 

  14. Miyayama S, Yamashiro Y, Hattori Y, Orito N, Matsui K, Tsuji K, et al. Microcoil embolization during abdominal vascular interventions through microcatheters with a tip of 2 French or less. Jpn J Radiol. 2011;29:286–90.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Diagnostic Radiology, Fukuiken Saiseikai Hospital, 7-1, Funabashi, Wadanaka-cho, Fukui, 918-8503, Japan

    Shiro Miyayama, Masashi Yamashiro, Masahiro Hashimoto, Miki Yoshida, Nanako Hashimoto, Masaya Ikuno & Kenichiro Okumura

  2. Department of Radiology, Kanazawa University Graduate School of Medical Science, 13-1, Takara-machi, Kanazawa, 920-8641, Japan

    Osamu Matsui

Authors
  1. Shiro Miyayama
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  2. Masashi Yamashiro
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  3. Masahiro Hashimoto
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  4. Miki Yoshida
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  5. Nanako Hashimoto
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  6. Masaya Ikuno
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  7. Kenichiro Okumura
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  8. Osamu Matsui
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Corresponding author

Correspondence to Shiro Miyayama.

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Miyayama, S., Yamashiro, M., Hashimoto, M. et al. Clinical features of hepatocellular carcinoma supplied by the left internal mammary artery. Jpn J Radiol 30, 798–805 (2012). https://doi.org/10.1007/s11604-012-0123-2

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  • DOI: https://doi.org/10.1007/s11604-012-0123-2

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