Literatur
McCullough PA, Roberts WC (2016) Influence of chronic renal failure on cardiac structure. J Am Coll Cardiol 67:1183–1185
Niu CY et al (2022) Sacubitril/Valsartan in patients with heart failure and concomitant end-stage kidney disease. J Am Heart Assoc 11(18):e026407
Haynes R et al (2020) Chronic kidney disease, heart failure and neprilysin inhibition. Nephrol Dial Transplant 35:558–564
McAlister FA et al (2012) Renal dysfunction in patients with heart failure with preserved versus reduced ejection fraction: impact of the new Chronic Kidney Disease-Epidemiology Collaboration Group formula. Circ Heart Fail 5:309–314
Ahmed A, Campbell RC (2008) Epidemiology of chronic kidney disease in heart failure. Heart Fail Clin 4:387–399
McMurray JJ et al (2014) Angiotensin-neprilysin inhibition versus enalapril in heart failure (Paradigm). N Engl J Med 371:993–1004
McDonagh TA et al (2021) 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 42:3599–3726
Heidenreich PA et al (2022) 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure. J Card Fail 28:e1–e167
Greene SJ et al (2018) Medical therapy for heart failure with reduced ejection fraction: the CHAMP-HF registry. J Am Coll Cardiol 72:351–366
Huitema AA et al (2020) Optimal usage of sacubitril/valsartan for the treatment of heart failure: the importance of optimizing heart failure care in Canada. CJC Open 2:321–327
Solomon SD et al (2019) Angiotensin–neprilysin inhibition in heart failure with preserved ejection fraction. N Engl J Med 381:1609–1620
Volpe M, Carnovali M, Mastromarino V (2016) The natriuretic peptides system in the pathophysiology of heart failure: From molecular basis to treatment. Clin Sci 130:57–77
Ayalasomayajula S, Langenickel T, Pal P, Boggarapu S, Sunkara G (2017) Clinical pharmacokinetics of sacubitril/valsartan (LCZ696): a novel angiotensin receptor-neprilysin inhibitor. Clin Pharmacokinet 56:1461–1478
https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/207620s018lbl.pdf
https://www.ema.europa.eu/en/documents/overview/entresto-epar-summary-public_en.pdf
Damman K et al (2018) Renal effects and associated outcomes during angiotensin-neprilysin inhibition in heart failure. JACC Heart Fail 6:489–498
Benigni A et al (2004) Vasopeptidase inhibitor restores the balance of vasoactive hormones in progressive nephropathy. Kidney Int 66:1959–1965
Davis BJ et al (2003) Renoprotective effects of vasopeptidase inhibition in an experimental model of diabetic nephropathy. Diabetologia 46:961–971
Taal MW et al (2001) Vasopeptidase inhibition affords greater renoprotection than angiotensin-converting enzyme inhibition alone. J Am Soc Nephrol 12:2051–2059
Cao Z et al (2001) Vasopeptidase inhibition attenuates the progression of renal injury in subtotal nephrectomized rats. Kidney Int 60:715–721
Spannella F, Giulietti F, Filipponi A, Sarzani R (2020) Effect of sacubitril/valsartan on renal function: a systematic review and meta-analysis of randomized controlled trials. ESC Heart Fail 7:3487–3496
Zhou W et al (2023) The efficacy and safety of sacubitril/valsartan in chronic kidney disease: a systematic review and meta-analysis. Int Urol Nephrol 56(1):181–190
Haynes R et al (2018) Effects of sacubitril/valsartan versus irbesartan in patients with chronic kidney disease: a randomized double-blind trial. Circulation 138:1505–1514
Jia R et al (2022) Effect of Sacubitril/Valsartan on renal function in patients with chronic kidney disease and heart failure with preserved ejection fraction: A real-world 12-week study. Eur J Pharmacol 928:175053
Vollmer Barbosa C, Lang H, Melk A, Schmidt BMW (2022) Renal events in patients receiving neprilysin inhibitors: a systematic review and meta-analysis. Nephrol Dial Transplant 37:2418–2428
Charkviani M, Krisanapan P, Thongprayoon C, Craici IM, Cheungpasitporn W (2024) Systematic review of cardiovascular benefits and safety of sacubitril-valsartan in end-stage kidney disease. Kidney Int Rep 9:39–51
Hsiao F‑C, Lin C‑P, Yu C‑C, Tung Y‑C, Chu P‑H (2022) Angiotensin receptor-neprilysin inhibitors in patients with heart failure with reduced ejection fraction and advanced chronic kidney disease: a retrospective multi-institutional study. Front Cardiovasc Med 9:794707
https://www.novartis.com/at-de/sites/novartis_at/files/FI_Entresto.pdf
Guo Y et al (2022) Effects of sacubitril/valsartan in ESRD patients undergoing hemodialysis with HFpEF. Front Cardiovasc Med 9:55780
Feng Z et al (2021) Pharmacokinetics and pharmacodynamics of sacubitril/valsartan in maintenance hemodialysis patients with heart failure. Blood Purif 51:270–279
Fu S et al (2021) Effects of sacubitril-valsartan in heart failure with preserved ejection fraction in patients undergoing peritoneal dialysis. Front Med 8:657067
Lee S et al (2020) Sacubitril/valsartan in patients with heart failure with reduced ejection fraction with end-stage of renal disease. ESC Heart Fail 7:1125–1129
Ma JW, Ren LL, Huang JC (2023) Efficacy of sacubitril/valsartan in peritoneal dialysis patients with HFpEF and its effect on residual renal function. Zhonghua Yi Xue Za Zhi 103:117–124
Wang B et al (2022) Effects of Sacubitril/Valsartan on resistant hypertension and myocardial work in hemodialysis patients. J of Clinical Hypertension 24:300–308
Lihua W, Cheng L, Chen H (2021) Use of angiotensin receptor neprilysin inhibitor in patients on maintenance hemodialysis with reduced cardiac ejection fraction, real-world experience from a single center. Iran J Kidney Dis 15:288–299
Martínez-Esteban MD et al (2022) Cardio-renal benefits of sacubitril/valsartan in patients with advanced chronic kidney disease: experience in daily clinical practice. BMC Nephrol 23:293
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Interessenkonflikt
C. Vollmer Barbosa gibt an, dass kein Interessenkonflikt besteht.
Für diesen Beitrag wurden von den Autor/-innen keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.
Additional information
Redaktion
Kirsten de Groot, Offenbach
Roland Schmitt, Hannover
Hinweis des Verlags
Der Verlag bleibt in Hinblick auf geografische Zuordnungen und Gebietsbezeichnungen in veröffentlichten Karten und Institutsadressen neutral.
QR-Code scannen & Beitrag online lesen
Rights and permissions
About this article
Cite this article
Vollmer Barbosa, C. Ist Sacubitril/Valsartan bei fortgeschrittener Nierenerkrankung und Dialysepflichtigkeit eine gute Option?. Nephrologie (2024). https://doi.org/10.1007/s11560-024-00731-4
Accepted:
Published:
DOI: https://doi.org/10.1007/s11560-024-00731-4