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Multi-templates surface molecularly imprinted polymer for rapid separation and analysis of quinolones in water

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Abstract

Rapid separation and analysis of trace quinolones (fleroxacin (FLRX), enoxacin (EN), norfloxacin (NOR), ciprofloxacin (CIP), enrofloxacin (ENRO), and lomefloxacin hydrochloride (LOME)) in real water samples were achieved by using a multi-templates molecularly imprinted polymer (MIP) based solid phase extraction (SPE) coupled with dispersive liquid-liquid microextraction (DLLME) followed by high performance liquid chromatography (HPLC). The MIP was prepared via surface molecular imprinting, using the selected quinolones as the templates and mesoporous silica modified magnetic graphene oxide as the carrier. The preparation and adsorption conditions were optimized. The MIP presented high adsorption capacity and wonderful selective recognition for the quinolones, with the adsorption capacities of 20.15, 20.88, 18.01, 20.01, 16.98, and 17.09 mg/g for FLRX, EN, NOR, CIP, ENRO, and LOME, respectively. Meanwhile, a SPE-DLLME-HPLC method for trace detection of FLRX, EN, NOR, CIP, ENRO, and LOME in real water samples was developed and showed outstanding applicability. The spiked recoveries and relative standard deviations (RSDs) were 89.67–100.5%, and 3.59–7.12%, respectively.

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Funding

This work was supported by the National Natural Science Foundation of China (No. 41272262), the Science and Technology Planning Project of Guangdong Province, China (No. 2016A040403112), and the Major Projects (Natural Science) of Education Department of Guangdong Province, China (261555101).

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  1. School of Environmental Science and Engineering, Guangdong University of Technology, 510006, Guangzhou, People’s Republic of China

    Yinming Fan, Guolong Zeng & Xiaoguo Ma

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  1. Yinming Fan
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  2. Guolong Zeng
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  3. Xiaoguo Ma
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Correspondence to Xiaoguo Ma.

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Fan, Y., Zeng, G. & Ma, X. Multi-templates surface molecularly imprinted polymer for rapid separation and analysis of quinolones in water. Environ Sci Pollut Res 27, 7177–7187 (2020). https://doi.org/10.1007/s11356-019-07437-4

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