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Obesity phenotypes are, in part, associated with physical activity in diabetic hemodialysis patients

  • Nephrology - Original Paper
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Abstract

Purpose

To investigate the prevalence of obesity phenotypes and their association with physical activity levels among diabetic hemodialysis patients.

Methods

This is a cross-sectional study with 84 diabetic hemodialysis patients (63.5 ± 9.4 years, 54.8% of men). Obesity was diagnosed as high body fat (≥ 40% for male and ≥ 30% for female). Sarcopenic obesity was considered if low skeletal muscle mass (< 20.0 kg for males and < 15.0 kg for females) and obesity were combined. Dynapenic obesity was defined in the presence of low handgrip strength (< 27 kg for males and < 16 kg for females) and obesity. Muscle failure obesity was confirmed in the concomitant presence of obesity, sarcopenia, and dynapenia. Physical activity level was assessed by the Baecke questionnaire and patients were classified as low physical activity according to the first tertile for each of and total domains.

Results

Fifty-four patients (64%) presented obesity. From these, 5 (6%), 19 (23%) and 8 (10%) were classified as sarcopenic obese, dynapenic obese, and muscle failure obese, respectively, and 22 (26%) were only obese. Patients with sarcopenic obesity and muscle failure obesity had lower leisure and locomotion physical activity scores than non-obese, whereas the total domain score did not differ across the groups. Muscle failure obesity was independently associated with low leisure physical activity (OR 10.8, 95% CI 1.3–88.1). Only sarcopenic obesity was independently associated with the locomotion and total physical activity domains (OR 15.4, 95% CI 1.4–90.2 and OR 17.0, 95% CI 1.5–95.4, respectively).

Conclusion

Our study found a lower prevalence of sarcopenic obesity compared to dynapenic obesity and muscle failure obesity among diabetic hemodialysis patients. Moreover, sarcopenic obesity and muscle failure obesity, but not dynapenic obesity, were associated with low physical activity levels.

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Acknowledgements

We would like to acknowledge the participants of our study and the Coordination of Superior Level Staff Improvement (CAPES) and the Programa de Excelência Acadêmica (PROEX) for supporting Clara Suemi da Costa Rosa with a Ph.D. scholarship.

Funding

This study did not receive any funding.

Author information

Authors and Affiliations

  1. Centro Universitário do Sagrado Coração (UNISAGRADO), Pró-reitoria de Pesquisa e Pós-graduação, Bauru, SP, Brazil

    Beatriz de Oliveira Matos, Natasha Maggi Marcos, Milene Peron Rodrigues Losilla & Camila Gimenes

  2. Universidade Estadual Paulista (UNESP), Faculdade de Ciências, Bauru, SP, Brazil

    Clara Suemi da Costa Rosa & Henrique Luiz Monteiro

  3. Faculty of Physical Education, University of Brasília, Brasília, Brazil

    Heitor Siqueira Ribeiro

  4. Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD), University of Maia, Porto, Portugal

    Heitor Siqueira Ribeiro

  5. UNESP-Instituto de Biociências, Campus de Rio Claro, Seção Técnica de Pós-graduação, Avenida 24-A no. 1515, Bairro Bela Vista, Rio Claro, SP, 13506-900, Brazil

    Clara Suemi da Costa Rosa

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  1. Beatriz de Oliveira Matos
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Correspondence to Clara Suemi da Costa Rosa.

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de Oliveira Matos, B., da Costa Rosa, C.S., Ribeiro, H.S. et al. Obesity phenotypes are, in part, associated with physical activity in diabetic hemodialysis patients. Int Urol Nephrol 54, 1751–1759 (2022). https://doi.org/10.1007/s11255-021-03060-w

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