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An easily available N-heterocyclic carbene–palladium(II) catalyst for Buchwald–Hartwig amination of aryl chlorides

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Abstract

An easily available N-heterocyclic carbene–palladium(II) complex was found to be an efficient catalyst for the Buchwald–Hartwig amination of aryl chlorides. Both secondary and primary amines were tolerated under the same reaction conditions. Under the optimal conditions, all reactions proceeded successfully to give the desired products in good to high yields within hours.

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Notes

  1. For early references on amination reactions see Negishi [9].

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Acknowledgments

We are grateful to the National Natural Sciences Foundation of China (Nos. U1404205 and 21202095), the Program for Science & Technology Innovation Talents in Universities of Henan Province (14HASTIT016) and Innovation Scientists and Technicians Troop Construction Projects of Henan Province for financial support.

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Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu, 476000, Henan, People’s Republic of China

    Tao Wang, Kai Xu, Lantao Liu, Huanping Xie, Ying Li & Wen-Xian Zhao

  2. College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450052, Henan, People’s Republic of China

    Huanping Xie & Wen-Xian Zhao

Authors
  1. Tao Wang
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  2. Kai Xu
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  3. Lantao Liu
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  4. Huanping Xie
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  5. Ying Li
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  6. Wen-Xian Zhao
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Corresponding authors

Correspondence to Lantao Liu or Wen-Xian Zhao.

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Wang, T., Xu, K., Liu, L. et al. An easily available N-heterocyclic carbene–palladium(II) catalyst for Buchwald–Hartwig amination of aryl chlorides. Transit Met Chem 41, 525–529 (2016). https://doi.org/10.1007/s11243-016-0048-1

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  • DOI: https://doi.org/10.1007/s11243-016-0048-1

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