For applications in tissue engineering, three-dimensional biodegradable polymeric matrices, whose surface is functionalized by nanoparticles obtained in the liquid phase by the method of laser ablation from bulk metal (Ag or Zn) targets, are synthesized by the method of aerodynamic synthesis from a solution of poly-l-lactide acid. Their properties are investigated. It is demonstrated that the matrices represent a very porous spatial fibrous structure consisting of polymorphic fibers with diameters from 0.25 to 2.5 μm. It is established that functional coatings consisting of agglomerates of semiconductor (ZnO) or metal (Ag) nanoparticles can be produced on the surface of structural matrix elements by repeated matrix impregnation.
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Translated from Izvestiya Vysshikh Uchebnykh Zavedenii, Fizika, No. 3, pp. 9–15, March, 2014.
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Bol’basov, E.N., Lapin, I.N., Tverdokhlebov, S.I. et al. Aerodynamic Synthesis of Biocompatible Matrices and their Functionalization by Nanoparticles Obtained by the Method of Laser Ablation. Russ Phys J 57, 293–300 (2014). https://doi.org/10.1007/s11182-014-0238-2
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DOI: https://doi.org/10.1007/s11182-014-0238-2