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Novel convenient one-pot method for the synthesis of indoloquinolines

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Abstract

A novel one-pot method based on the sequence of the Fisher reaction between nitroacetophenone and phenylhydrazines, the reduction with metallic tin directly in polyphosphoric acid, and acylation has been developed for the synthesis of indoloquinolines. The obtained indolo-[3,2-c]quinolines are precursors of the analogs of isocryptolepine alkaloid.

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Authors and Affiliations

  1. North Caucasus Federal University, 1A ul. Pushkina, 355009, Stavropol, Russian Federation

    N. A. Aksenov, A. Z. Gasanova, I. V. Aksenova & A. V. Aksenov

  2. Dagestan State Technical University, 70 ul. Imama Shamilya, 367010, Makhachkala, Russian Federation

    G. M. Abakarov

Authors
  1. N. A. Aksenov
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  2. A. Z. Gasanova
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  3. G. M. Abakarov
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  4. I. V. Aksenova
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  5. A. V. Aksenov
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Correspondence to N. A. Aksenov.

Additional information

Based on the materials of the V All-Russian Organic Chemistry Conference (ROCC-V) (September 10–14, 2018, Vladikavkaz, Russia).

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 4, pp. 0836–0840, April, 2019.

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Aksenov, N.A., Gasanova, A.Z., Abakarov, G.M. et al. Novel convenient one-pot method for the synthesis of indoloquinolines. Russ Chem Bull 68, 836–840 (2019). https://doi.org/10.1007/s11172-019-2493-4

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  • DOI: https://doi.org/10.1007/s11172-019-2493-4

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