Abstract
1,2,3-Thiadiazolylureas containing amino acid residues were synthesized. These compounds were converted to 5-sulfanyl-1,2,3-triazol-1-ylaminocarboxylic acid sodium salts under alkaline conditions. These salts were found to inhibit the oxidation of ascorbic acid with air oxygen. In the presence of the equimolar amount of 5-sulfanyl-1,2,3-triazoles, the rate of diminution of ascorbic acid decreased by 1.5—3 times, whereas in the case of their two-fold excess by a factor of 5.
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 0203—0208, January, 2016.
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Emelianov, V.V., Musalnikova, A.V., Savateeva, E.A. et al. Synthesis and evaluation of the influence of 5-sulfanyl-1,2,3-triazol-1-ylaminocarboxylic acid derivatives on kinetics of ascorbic acid oxidation. Russ Chem Bull 65, 203–208 (2016). https://doi.org/10.1007/s11172-016-1285-3
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DOI: https://doi.org/10.1007/s11172-016-1285-3