3,4-Substituted-(4H)-1,2,4-triazole-5-thiols were synthesized and used for S-alkylation, cyanoethylation, and aminomethylation to produce a series of new 1,2,4-triazole derivatives of interest as biologically active compounds. The antitumor properties of several of the 1,2,4-triazole derivatives were studied.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 52, No. 5, pp. 22 – 25, May, 2018.
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Ovsepyan, T.R., Dilanyan, S.V., Arsenyan, F.G. et al. New 3-(4-Propoxybenzyl)-5-Sulfanyl-Substituted (4H)-1,2,4-Triazoles and Their Antitumor Activity. Pharm Chem J 52, 404–407 (2018). https://doi.org/10.1007/s11094-018-1830-5
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DOI: https://doi.org/10.1007/s11094-018-1830-5