The fresh flowers of Opuntia stricta were collected and extracted with 85% methanol under reflux. The concentrated extract was fractionated with Et2O, EtOAc and petroleum ether. Rhamnetin 3-O-rutinoside was obtained from EtOAc fraction, as confirmed through 1H and 13C NMR, 1H-1H NOESY, 1H-13C HSQC, and mass spectra. The isolated flavonoid glycoside was investigated for its antihyperglycemic activity on alloxan-induced diabetic male albino rats.
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References
The wealth of India: Raw Materials, CSIR, New Delhi, 7,100 (1966).
I. Chandrasekaran, H. A. Khan, and A. Ghanin, Plant. Med., 43, 310 (1981).
K. Venkataraman, T. A. Geissman, The Chemistry of Flavonoid compounds, Pergamon Press, London, 1962, p._48.
D.W. Fox,W. L. Savage, and S. H.Wendes, J. Am. Chem. Soc. , 75, 2504 (1953).
A. F. Mohun and I. J. Y. Cook, J. Clin. Pathol., 15, 169 (1962).
B. Halliwell and J. M. C. Gutteridge, Free Radicals in Biology and Medicine, Oxford University Press, Oxford, UK, 1985, p. 208.
T. Agarwal and J. S. Tiwari, J. Indian. Chem. Soc., 68, 479 (1991).
P. Satyanarayana, K. Subrahmanyam, N. Viswanatham, and R. S. Ward, J. Nat. Prod., 51, 44 (1988).
S. Dhandapani, V. Ramasamy, S. Rajagopal, N. Namasivayam, Pharmacological Research , 46, 251 (2002).
K. N. Bopanna, J. Kannan, G. Sushma, R. Balaraman, S. P. Rathod, Indian. J. Pharmacol , 29, 162 (1997).
G. Lopez-Berestein, V. Fainsteine, R. Hopfer, K. Mehta, U. P. Hersh, Y. Reuben, R. L. Juliano, G. P. Bodey, J. Infect. Dis., 151, 704 (1985).
The Chemistry of flavonoid Compounds, T. A. Geissman (Ed.), Pergmon Press, London, 1963, p._13 – 63.
L. Zechmister, Progress in Chemistry of Organic Natural Products, Springer, Wien, 1967, p. 107.
L. Jurd, Arch. Biochem. Biophys., 63, 376 (1956).
K. R. Markham, T. J. Mabry, T. A. Geissman, and E. Hinreiner, The flavonoids, Chapman and Hall, London, 1975, p. 70.
T. J. Mabry, K. R. Markham, and M. B. Thomas, The Systematic Identification of Flavonoids, Springer-Verlag, 1970, p. 271.
R. E. Mitchell and T. A. Geissman, Phytochemistry, 10, 1559 (1971).
D. G. I. Kingston, Tetrahedron, 27, 2691 (1971).
R. D. Schimid, Tetrahedron, 24, 3697, (1968).
M. P. Stanley and V. P. Menon, J. Ethans Pharmacol., 70, 9 (2000).
H. Wagner, M. A. Iyengar, and L. Hçrhammer, Phytochemistry, 12, 2548 (1973).
P. T. Mathew and K. T. Aswati, Indian J. Biochem. Biophys., 10, 154 (1973).
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An erratum to this article can be found at http://dx.doi.org/10.1007/s11094-011-0668-x
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Merina, A.J., Kesavan, D. & Sulochana, D. Isolation and antihyperglycemic activity of flavonoid from flower petals of Opuntia stricta . Pharm Chem J 45, 317–321 (2011). https://doi.org/10.1007/s11094-011-0625-8
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DOI: https://doi.org/10.1007/s11094-011-0625-8