Abstract
Stereoselective synthesis of an optically active menthyl ester of 2-chloroethoxy-4′-dimethylaminophenylphosphorylacetic acid (CAPAM) is described. The product structure was confirmed by elemental analyses and IR, NMR (1H, 13C, 31P), and mass spectroscopy measurements. When tested for neuropharmacological properties, CAPAM exhibited a neurotropic (deprivating) activity and myorelaxant action.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 40, No. 9, pp. 9–11, September, 2006.
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Tarasova, R.I., Voskresenskaya, O.V., Eliseenkova, R.M. et al. Stereoselective synthesis and neurotropic activity of phosphorylacetic acid derivatives. Pharm Chem J 40, 469–472 (2006). https://doi.org/10.1007/s11094-006-0156-x
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DOI: https://doi.org/10.1007/s11094-006-0156-x