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Design of steering shaped optically transparent biosensor for the detection of tuberculosis cells

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Abstract

This work synthesizes a five-zonal steering-based PCF structure for detecting tuberculosis cells. The proposed steering-based five-zonal structure (SBFZ_PCF) comprises silica along with circular air holes in the core and an array of circular air holes with five polygons arranged in an alternative fashion in the cladding area. This paper aims to provide an in-depth and lucid view of the structure designing and simulation using COMSOL Multiphysics_Version_5.3 and perform elaborative numerical analysis by full-vector finite element method. The performance metrics yield the investigated wavelength region between 1.7 to 2.6 μm for computing optical parameters including Sensitivity, confinement loss (CL), Numerical Aperture (NA), Effective Area (Aeff), and Divergence. The numerical analysis demonstrates the maximum relative sensitivity of 89% at a very low confinement loss. The numerical aperture is investigated for assessment of the light acceptance of the proposed tuberculosis sensor. Hence our presented sensor quantitatively supports better sensitivity with all improved parameters. The proposed structure empirically proves and accomplishes label-free bio-sensing in tuberculosis cell detection along with other bio-medical applications.

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References

  • Abdelghaffar, M., Gamal, Y., El-Khoribi, R.A., Soliman, W., Badr, Y., Hameed, M.F.O., Obayya, S.S.A.: Highly sensitive V-shaped SPR PCF biosensor for cancer detection. Opt. Quant. Electron. 55(5), 472 (2023)

    Google Scholar 

  • Ahmed, K., Morshed, M., Asaduzzaman, S., Arif, M.F.H.: Optimization and enhancement of liquid analyte sensing performance based on square-cored octagonal photonic crystal fiber. Optik 131, 687–696 (2017a)

    ADS  Google Scholar 

  • Ahmed, K., Islam, M., Sen, S., Paul, B.K., Chowdhury, S., Hasan, M., Uddin, M.S., Asaduzzaman, S., Bahar, A.N.: Low-loss single mode terahertz microstructure fiber with near-zero-flattened dispersion. Adv. Sci. Eng. Med. 9(10), 829–836 (2017b)

    Google Scholar 

  • Ahmed, K., Haque, M.J., Jabin, M.A., Paul, B.K., Amiri, I.S., Yupapin, P.: Tetra-core surface plasmon resonance based biosensor for alcohol sensing. Phys. B 570, 48–52 (2019a)

    ADS  Google Scholar 

  • Ahmed, K., Paul, B.K., Vasudevan, B., Rashed, A.N.Z., Maheswar, R., Amiri, I.S., Yupapin, P.: Design of D-shaped elliptical core photonic crystal fiber for blood plasma cell sensing application. Results Phys. 12, 2021–2025 (2019b)

    ADS  Google Scholar 

  • Ahmed, F., Roy, S., Ahmed, K., Paul, B.K., Bahar, A.N.: A novel star shape photonic crystal fiber for low loss terahertz pulse propagation. Nano Commun. Netw. 19, 26–32 (2019c)

    Google Scholar 

  • Ahmed, K., Ahmed, F., Roy, S., Paul, B.K., Aktar, M.N., Vigneswaran, D., Islam, M.S.: Refractive index-based blood components sensing in terahertz spectrum. IEEE Sens. J. 19(9), 3368–3375 (2019d)

    ADS  Google Scholar 

  • Ahmed, F., Roy, S., Paul, B.K., Ahmed, K., Bahar, A.N.: Extremely low loss of photonic crystal fiber for terahertz wave propagation in optical communication applications. J. Opt. Commun. 41(4), 393–401 (2020)

    Google Scholar 

  • Ahmed, K., Amin, R., Bui, F.M., Chen, L., Mohammadd, N., Al-Zahrani, F.A., Kumar, S.: Design and analysis of multi-analyte detection based biosensor in the visible to near-infrared (VNIR) region. IEEE Trans. Nanobiosci. (2023). https://doi.org/10.1109/TNB.2023.3281527

    Article  Google Scholar 

  • Aly, A.H., Mohamed, D., Zaky, Z.A., Matar, Z.S., Abd El-Gawaad, N.S., Shalaby, A.S., Tayeboun, F., Mohaseb, M.: Novel biosensor detection of tuberculosis based on photonic band gap materials. Mater. Res. (2021). https://doi.org/10.1590/1980-5373-MR-2020-0483

    Article  Google Scholar 

  • American Thoracic Society: Diagnostic standards and classification of tuberculosis in adults and children. Am. J. Respir. Crit. Care Med. 161, 1376–1395 (2000)

    Google Scholar 

  • Amin, R., Abdulrazak, L.F., Tahhan, S.R., Mohammadd, N., Ahmed, K., Bui, F.M., Ibrahim, S.M.: Tellurite glass based optical fiber for the investigation of supercontinuum generation and nonlinear properties. Phys. Scr. 97(3), 030007 (2022)

    ADS  Google Scholar 

  • An, Z., Jang, C.H.: Nanoparticle-assisted optical sensor for clinical diagnosis of tuberculosis. Microchem. J. 147, 941–947 (2019)

    Google Scholar 

  • Asaduzzaman, S., Rehana, H., Chakma, R., Faragallah, O.S., El-Sayed, H.S., Eid, M.M., Rashed, A.N.Z.: Hexa-sectored square photonic crystal fiber for blood serum and plasma sensing with ultralow confinement loss. Appl. Phys. A 128(6), 467 (2022)

    ADS  Google Scholar 

  • Atakaramians, S., Afshar, S., Ebendorff-Heidepriem, H., Nagel, M., Fischer, B.M., Abbott, D., Monro, T.M.: THz porous fibers: design, fabrication and experimental characterization. Opt. Express 17(16), 14053–14062 (2009)

    ADS  Google Scholar 

  • Atiqullah, S.M., Palit, A., Reja, M.I., Akhtar, J., Fatema, S., Absar, R.: Detection of harmful food additives using highly sensitive photonic crystal fiber. Sens. Bio-Sens. Res. 23, 100275 (2019)

    Google Scholar 

  • Balamurugan, A.M., Parvin, T., Alsalem, K.A.J., Ibrahim, S.M.: Refractive index based optically transparent biosensor device design for early detection of coronavirus. Opt. Quant. Electron. 55(6), 507 (2023)

    Google Scholar 

  • Bise, R.T., Trevor, D.J.: Sol–gel derived microstructured fiber: fabrication and characterization. In: Optical Fiber Communication Conference, p. OWL6. Optica Publishing Group (2005)

  • Blumberg, H.M., et al.: American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America: treatment of tuberculosis. Am. J. Respir. Crit. Care Med. 167, 603–662 (2003)

    Google Scholar 

  • Bulbul, A.A., Jibon, R.H., Das, S.K., Roy, T., Saha, A., Hossain, M.B.: PCF based formalin detection by exploring the optical properties in THz regime. Nanosci. Nanotechnol. Asia 11(3), 314–321 (2021)

    Google Scholar 

  • Ebendorff-Heidepriem, H., Schuppich, J., Dowler, A., Lima-Marques, L., Monro, T.M.: 3D-printed extrusion dies: a versatile approach to optical material processing. Opt. Mater. Express 4(8), 1494–1504 (2014)

    ADS  Google Scholar 

  • Fatema, S., Absar, R., Istiaque Reja, M., Akhtar, J.: Effect of soft glass rod infiltration in the core of photonic crystal fiber. J. Opt. Commun. 41(4), 371–383 (2020)

    Google Scholar 

  • Ghazanfari, A., Li, W., Leu, M.C., Hilmas, G.E.: A novel freeform extrusion fabrication process for producing solid ceramic components with uniform layered radiation drying. Addit. Manuf. 15, 102–112 (2017)

    Google Scholar 

  • Habib, M.A., Anower, M.S., Hasan, M.R.: Highly birefringent and low effective material loss microstructure fiber for THz wave guidance. Opt. Commun. 423, 140–144 (2018)

    ADS  Google Scholar 

  • Habib, M.A., Anower, M.S., Abdulrazak, L.F., Reza, M.S.: Hollow core photonic crystal fiber for chemical identification in terahertz regime. Opt. Fiber Technol. 52, 101933 (2019)

    Google Scholar 

  • Hossain, M.B., Podder, E.: Design and investigation of PCF-based blood components sensor in terahertz regime. Appl. Phys. A 125(12), 861 (2019)

    ADS  Google Scholar 

  • Hossain, M.N., Tanvir, J., Aktar, M.N., Ahmed, K.: Design of a fuel adulteration detector sensor based on surface plasmon resonance. Opt. Quant. Electron. 55(1), 61 (2023a)

    Google Scholar 

  • Hossain, M.B., Kříž, J., Dhasarathan, V., Rahaman, M.E.: Photonic crystal fiber (PhCF) for petrochemical sensing. Front. Phys. 10, 1390 (2023b)

    Google Scholar 

  • Islam, M.I., Ahmed, K., Asaduzzaman, S., Paul, B.K., Bhuiyan, T., Sen, S., Islam, M.S., Chowdhury, S.: Design of single mode spiral photonic crystal fiber for gas sensing applications. Sens. Bio-Sens. Res. 13, 55–62 (2017a)

    Google Scholar 

  • Islam, M.S., Sultana, J., Ahmed, K., Islam, M.R., Dinovitser, A., Ng, B.W.H., Abbott, D.: A novel approach for spectroscopic chemical identification using photonic crystal fiber in the terahertz regime. IEEE Sens. J. 18(2), 575–582 (2017b)

    ADS  Google Scholar 

  • Islam, M.S., Paul, B.K., Ahmed, K., Asaduzzaman, S., Islam, M.I., Chowdhury, S., Sen, S., Bahar, A.N.: Liquid-infiltrated photonic crystal fiber for sensing purpose: design and analysis. Alex. Eng. J. 57(3), 1459–1466 (2018)

    Google Scholar 

  • Jabin, M.A., Ahmed, K., Rana, M.J., Paul, B.K., Islam, M., Vigneswaran, D., Uddin, M.S.: Surface plasmon resonance based titanium coated biosensor for cancer cell detection. IEEE Photonics J. 11(4), 1–10 (2019a)

    Google Scholar 

  • Jabin, M.A., Ahmed, K., Rana, M.J., Paul, B.K., Luo, Y., Vigneswaran, D.: Titanium-coated dual-core D-shaped SPR-based PCF for hemoglobin sensing. Plasmonics 14(6), 1601–1610 (2019b)

    Google Scholar 

  • Jepsen, P.U., Møller, U., Merbold, H.: Investigation of aqueous alcohol and sugar solutions with reflection terahertz time-domain spectroscopy. Opt. Express 15(22), 14717–14737 (2007)

    ADS  Google Scholar 

  • Khalaf, M.K., Tahhan, S.R., Taher, H.J., Ibrahim, S.M., Ahmed, K.: Au-TiO2 coated dielectric micro-channel based plasmonic refractive index sensor. Opt. Quant. Electron. 55(7), 612 (2023)

    Google Scholar 

  • Mohammadd, N., Abdulrazak, L.F., Tahhan, S.R., Amin, R., Ibrahim, S.M., Ahmed, K., Bui, F.M.: GaP-filled PCF with ultrahigh birefringence and nonlinearity for distinctive optical applications. J. Ovonic Res. 18(2), 129–140 (2022)

  • Nagel, M., Haring Bolivar, P., Brucherseifer, M., Kurz, H., Bosserhoff, A., Büttner, R.: Integrated THz technology for label-free genetic diagnostics. Appl. Phys. Lett. 80(1), 154–156 (2002)

    ADS  Google Scholar 

  • Parvin, T., Ahmed, K., Alatwi, A.M., Rashed, A.N.Z.: Differential optical absorption spectroscopy-based refractive index sensor for cancer cell detection. Opt. Rev. 28, 134–143 (2021)

    Google Scholar 

  • Perkins, M.D.: New diagnostic tools for tuberculosis [The Eddie O’Brien Lecture]. Int. J. Tuberc. Lung Dis. 4(12), S182–S188 (2000)

    Google Scholar 

  • Podder, E., Hossain, M.B., Ahmed, K.: Photonic crystal fiber for milk sensing. Sens. Bio-Sens. Res. 38, 100534 (2022)

    Google Scholar 

  • Ramanujam, N.R., Patel, S.K., Reddy, N.M., Taya, S.A., Vigneswaran, D., Rajan, M.M.: One-dimensional ring mirror-defect photonic crystal for detection of mycobacterium tuberculosis bacteria. Optik 219, 165097 (2020)

    ADS  Google Scholar 

  • Reddy, N.M.: A study on refractive index of plasma of blood of patients suffering from tuberculosis. Int. J. Innov. Technol. Creat. Eng. 2(8), 23 (2012)

    Google Scholar 

  • Sen, S., Chowdhury, S., Ahmed, K., Asaduzzaman, S.: Design of a porous cored hexagonal photonic crystal fiber based optical sensor with high relative sensitivity for lower operating wavelength. Photonic Sens. 7, 55–65 (2017)

    ADS  Google Scholar 

  • Srivastava, S.K., Van Rijn, C.J., Jongsma, M.A.: Biosensor-based detection of tuberculosis. RSC Adv. 6(22), 17759–17771 (2016)

    ADS  Google Scholar 

  • Sultana, J., Islam, M.S., Ahmed, K., Dinovitser, A., Ng, B.W.H., Abbott, D.: Terahertz detection of alcohol using a photonic crystal fiber sensor. Appl. Opt. 57(10), 2426–2433 (2018)

    ADS  Google Scholar 

  • Tanvir, J., Ahmed, K., Bui, F.M., Patel, S.K.: A study on graphene-based sensor devices. In: Recent Advances in Graphene Nanophotonics, pp. 69–82. Springer Nature Switzerland, Cham (2023a)

  • Tanvir, J., Mitu, S.A., Tahhan, S.R., Ahmed, K., Bui, F.M., Patel, S.K., Al-Zahrani, F.A.: Terahertz spectroscopic based bending effect inspection on hollow-core anti-resonant fiber. Opt. Quant. Electron. 55(4), 305 (2023b)

    Google Scholar 

  • Vijayalakshmi, D., Ayyanar, N., Manimegalai, C.T., Alzahrani, F.A.: Photonic crystal fiber-based biosensor for detection of women reproductive hormones. Opt. Quant. Electron. 55(5), 442 (2023)

    Google Scholar 

  • World Health Organization: Global tuberculosis control: surveillance, planning, financing: WHO report 2005. World Health Organization (2005)

  • World Health Organization: World health statistics 2015. World Health Organization (2015)

  • Yu, C., Fan, S., Sun, Y., Pickwell-MacPherson, E.: The potential of terahertz imaging for cancer diagnosis: a review of investigations to date. Quant. Imaging Med. Surg. 2(1), 33 (2012)

    Google Scholar 

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Authors and Affiliations

  1. Department of Electronics and Communication Engineering, National Institute of Technology Patna, Patna, Bihar, 800005, India

    Tarunnum Parvin, V K Jagadeesh & Syed Shahnawazuddin

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  1. Tarunnum Parvin
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  2. V K Jagadeesh
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  3. Syed Shahnawazuddin
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Contributions

Conceptualization, Data curation, Formal analysis, Investigation, Methodology, TP; Funding acquisition, Project administration, Resources, Software, Supervision, Validation, JVK, SS; Visualization, Writing—original draft, Writing—review editing, TP; JVK, SS.

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Correspondence to V K Jagadeesh.

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Parvin, T., Jagadeesh, V.K. & Shahnawazuddin, S. Design of steering shaped optically transparent biosensor for the detection of tuberculosis cells. Opt Quant Electron 55, 842 (2023). https://doi.org/10.1007/s11082-023-05071-6

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