The morphological characteristics of neurons containing 200-kDal neurofilaments (NF200+) were studied in the sensory ganglia of the thoracic and lumbar spinal nerves during the first year of life in rats (n = 80). Treatment of neonatal rat pups with capsaicin (150 mg/kg) altered the developmental dynamics of NF200+ neurons, with a decrease in the numbers and mean cross-sectional areas of these neurons in both ganglia. Segmental differences consisted of large decreases in the number of NF200+ neurons in the sensory ganglia of the lumbar spinal nerve in the early and late periods of life.
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Translated from Morfologiya, Vol. 142, No. 4, pp. 37–42, July–August, 2012.
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Porseva, V.V., Shilkin, V.V., Korzina, M.B. et al. Developmental Changes in NF200+ Neurons in Sensory Ganglia at Different Segmental Levels on Chemical Deafferentation. Neurosci Behav Physi 43, 602–606 (2013). https://doi.org/10.1007/s11055-013-9779-z
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DOI: https://doi.org/10.1007/s11055-013-9779-z