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The Content of Peripheral and Integral Proteins in Vertebrate Brain Microsomal Membranes

  • Comparative and Ontogenic Biochemistry and Immunology
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Abstract

The content of peripheral and integral proteins in brain microsomal membranes in 11 species of vertebrates is studied. The amount of peripheral proteins does not exceed one third of the total protein, whereas integral proteins account for the main mass of proteins of microsomal membranes in the brain of animals at all levels of the vertebrate organization. Predominance of integral proteins can be considered as an indicator of a significant rigidity, high stability of brain membranes, and predominance in neuronal membranes of complex receptor proteins, ion channels and pumps, as well as ion exchangers. Microsomal membranes in the brain of reptiles are characterized by a higher content of peripheral and integral Triton-soluble proteins in comparison with other classes of animals. The possibility to use data on chemical composition of the brain microsomal membranes for study of congener relationships of vertebrates is considered.

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  1. Central Research Laboratory, Samara State Medical University, Samara, Russia

    T. N. Medvedeva

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  1. T. N. Medvedeva
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__________

Translated from Zhurnal Evolyutsionnoi Biokhimii i Fiziologii, Vol. 41, No. 2, 2005, pp. 125–128.

Original Russian Text Copyright © 2005 by Medvedeva.

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Medvedeva, T.N. The Content of Peripheral and Integral Proteins in Vertebrate Brain Microsomal Membranes. J Evol Biochem Phys 41, 157–161 (2005). https://doi.org/10.1007/s10893-005-0049-8

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  • DOI: https://doi.org/10.1007/s10893-005-0049-8

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