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A New N,N-Dimethyl Purine from an Australian Dictyoceratid Sponge

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Abstract

N6-methyl mucronatine (C8H12N5O) has been isolated from a dictyoceratid sponge collected in South East Queensland. The solid state structure of the new metabolite (I) was confirmed by X-ray crystallography, while an NMR study in d 4-MeOH reveals the presence of a minor tautomer identified as (II).

Graphical Abstract

The crystal structure of the purine N10-methyl mucronatine (C8H12N5O) is reported, isolated from a dictyoceratid sponge collected in South East Queensland, Australia

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Acknowledgments

We thank the University of Queensland and the Australia Research Council for financial support. The assistance of Sharna K. Graham and Daniel Holdsworth with sample collection, and Mr Graham McFarlane for mass spectrometry is gratefully acknowledged. Permission to collect sponge samples was provided by the Queensland Department of Primary Industries and Fisheries.

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Authors and Affiliations

  1. School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, 4072, Australia

    Suciati, Mary J. Garson & Paul V. Bernhardt

  2. Centre for Advanced Imaging, The University of Queensland, Brisbane, 4072, Australia

    Gregory K. Pierens

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  1. Suciati
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  2. Mary J. Garson
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  3. Paul V. Bernhardt
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  4. Gregory K. Pierens
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Correspondence to Mary J. Garson or Paul V. Bernhardt.

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Suciati, Garson, M.J., Bernhardt, P.V. et al. A New N,N-Dimethyl Purine from an Australian Dictyoceratid Sponge . J Chem Crystallogr 41, 1669–1672 (2011). https://doi.org/10.1007/s10870-011-0155-y

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  • DOI: https://doi.org/10.1007/s10870-011-0155-y

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