A new eudesmanolide, macrocephalolide I (1), along with 11 known compounds 2–12, were isolated from the whole plant of Artemisia macrocephala. Their structures were elucidated by HR-ESI-MS, NMR, and ECD calculations. Compound 1 was tested for anti-inflammatory and anti-tumor activities, without obvious potentials unfortunately. Compounds 2–12 were isolated firstly from Artemisia macrocephala, wherein 8, 11 were isolated from Artemisia genus for the first time.
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This work was supported by the National Natural Science Foundation of China (Grant No. U1703235).
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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2023, pp. 425–427.
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Zhao, Y.R., Aisa, H.A. & Zou, G.A. Chemical Constituents from Artemisia macrocephala. Chem Nat Compd 59, 502–504 (2023). https://doi.org/10.1007/s10600-023-04035-2
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DOI: https://doi.org/10.1007/s10600-023-04035-2