Amides of betulonic and oleanonic acids with diethylenetriamine, triethylenetetramine, and spermidine were synthesized. Antitumor activity in vitro was not found for the conjugate of betulonic acid with diethylenetriamine.
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Acknowledgment
The work was supported financially by the RFBR (Project No. 08-03-00868). We thank the National Cancer Institute (NCI) for determining the antitumor activity of 3 in vitro.
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Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 62–65, January–February, 2011.
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Giniyatullina, G.V., Kazakova, O.B., Salimova, E.V. et al. Synthesis of new betulonic and oleanonic acid amides. Chem Nat Compd 47, 68–72 (2011). https://doi.org/10.1007/s10600-011-9832-5
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DOI: https://doi.org/10.1007/s10600-011-9832-5