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The synthesis of 3-nitro-4H-benzo[h]chromenes

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Chemistry of Heterocyclic Compounds Aims and scope

A method for the synthesis of 3-nitro-4H-benzo[h]chromenes was developed based on the reaction of 1-naphthoquinone 2-methides generated in situ from Mannich bases with 4-(2-nitrovinyl)morpholine. It was shown that such nucleophiles as morpholine and 4-bromoaniline add to the double bond of the pyran ring.

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Authors and Affiliations

  1. Samara State Technical University, 244 Molodogvardeyskaya St, Samara, 443100, Russia

    Dmitry V. Osipov, Alina A. Artemenko, Pavel E. Krasnikov & Vitaly A. Osyanin

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  1. Dmitry V. Osipov
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  2. Alina A. Artemenko
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  3. Pavel E. Krasnikov
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  4. Vitaly A. Osyanin
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Correspondence to Vitaly A. Osyanin.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2023, 59(4/5), 249–253

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Osipov, D.V., Artemenko, A.A., Krasnikov, P.E. et al. The synthesis of 3-nitro-4H-benzo[h]chromenes. Chem Heterocycl Comp 59, 249–253 (2023). https://doi.org/10.1007/s10593-023-03189-9

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