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4-hydroxy-2-quinolones. 96. Synthesis and properties of 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Alkaline hydrolysis of the ethyl ester of 4-(cyanoethoxycarbonylmethyl)-2-oxo-1,2-dihydroquinoline-3-carboxylic acid is accompanied by decarboxylation with loss of two molecules of CO2 and leads to 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid.

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Authors and Affiliations

  1. National Pharmaceutical University, Kharkov, 61002, Ukraine

    I. V. Ukrainets, L. V. Sidorenko & O. V. Gorokhova

  2. Institute of Scintillation Compounds, National Academy of Sciences of Ukraine, Kharkov, 61001

    S. V. Shishkina

Authors
  1. I. V. Ukrainets
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  2. L. V. Sidorenko
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  3. O. V. Gorokhova
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  4. S. V. Shishkina
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 887–893, June, 2006.

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Ukrainets, I.V., Sidorenko, L.V., Gorokhova, O.V. et al. 4-hydroxy-2-quinolones. 96. Synthesis and properties of 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid. Chem Heterocycl Compd 42, 776–781 (2006). https://doi.org/10.1007/s10593-006-0160-9

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  • DOI: https://doi.org/10.1007/s10593-006-0160-9

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