Abstract
It has been found that 2,3-dioxopyrrolo[2,1-a]isoquinolines react with aromatic amines in glacial acetic acid and with heteroaromatic and secondary aliphatic amines in the absence of acid with opening of the pyrroledione ring to give 1,2,3,4-tetrahydroisoquinoline enamino ketoamides.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1378–1382, September, 2005.
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Polygalova, N.N., Mikhailovskii, A.G. Reaction of 2,3-Dioxopyrrolo-[2,1-a]isoquinolines with Aromatic and Secondary Aliphatic Amines. Chem Heterocycl Compd 41, 1173–1177 (2005). https://doi.org/10.1007/s10593-005-0298-x
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DOI: https://doi.org/10.1007/s10593-005-0298-x