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Low-dose coronary-CT angiography using step and shoot at any heart rate: comparison of image quality at systole for high heart rate and diastole for low heart rate with a 128-slice dual-source machine

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Abstract

To compare image quality of coronary CT angiography in step-and-shoot mode at the diastolic phase at low heart rates (<70 bpm) and systolic phase at high heart rates (≥70 bpm). We prospectively included 96 consecutive patients then excluded 5 patients with arrhythmia. Coronary CT-angiography was performed using a dual-source 128-slice CT machine, at the diastolic phase in the 55 patients with heart rates <70 bpm (group D) and at the systolic phase in the 36 patients with heart rates ≥70 (group S). Image quality was scored on a 5 point-scale (1, not interpretable; 2, insufficient for diagnosis; 3, fair, sufficient for diagnosis; 4, good; 5, excellent). In addition, we compared the number of stair-step artifacts in the two groups. Mean image quality score was 4 (0.78) in group D and 4.1 (0.34) in group S (NS), with an unequal distribution (p = 0.01). Step artifacts were seen in 44 % of group D and 18 % of group S patients (p = 0.02). In 3 group D patients and no group S patients, the image score was <3 due to artifacts, requiring repeat CT-angiography. When performing dual-source 128-slice CT-angiography, step-and-shoot acquisition provides comparable mean image quality in systole, with less variability and fewer stair-step artifacts, compared to diastole. This method may be feasible at any heart rate in most patients in sinus rhythm, allowing low-dose prospective acquisition without beta-blocker premedication.

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References

  1. Poll LW, Cohnen M, Brachten S, Ewen K, Modder U (2002) Dose reduction in multi-slice CT of the heart by use of ECG-controlled tube current modulation (“ECG pulsing”): phantom measurements. Rofo 174(12):1500–1505

    Article  PubMed  CAS  Google Scholar 

  2. Flohr TG, Schoepf UJ, Kuettner A, Halliburton S, Bruder H, Suess C, Schmidt B, Hofmann L, Yucel EK, Schaller S, Ohnesorge BM (2003) Advances in cardiac imaging with 16-section CT systems. Acad radiol 10(4):386–401

    Article  PubMed  Google Scholar 

  3. Hausleiter J, Meyer T, Hermann F, Hadamitzky M, Krebs M, Gerber TC, McCollough C, Martinoff S, Kastrati A, Schomig A, Achenbach S (2009) Estimated radiation dose associated with cardiac CT angiography. JAMA 301(5):500–507

    Article  PubMed  CAS  Google Scholar 

  4. Abada HT, Larchez C, Daoud B, Sigal-Cinqualbre A, Paul JF (2006) MDCT of the coronary arteries: feasibility of low-dose CT with ECG-pulsed tube current modulation to reduce radiation dose. AJR Am J Roentgenol 186(6 Suppl 2):S387–S390

    Article  PubMed  Google Scholar 

  5. Arnoldi E, Johnson TR, Rist C, Wintersperger BJ, Sommer WH, Becker A, Becker CR, Reiser MF, Nikolaou K (2009) Adequate image quality with reduced radiation dose in prospectively triggered coronary CTA compared with retrospective techniques. Eur Radiol 19(9):2147–2155

    Article  PubMed  Google Scholar 

  6. Stolzmann P, Goetti R, Baumueller S, Plass A, Falk V, Scheffel H, Feuchtner G, Marincek B, Alkadhi H, Leschka S (2011) Prospective and retrospective ECG-gating for CT coronary angiography perform similarly accurate at low heart rates. Eur J Radiol 79(1):85–91. doi:10.1016/j.ejrad.2009.12.016

    Article  PubMed  Google Scholar 

  7. Wu W, Budovec J, Foley WD (2009) Prospective and retrospective ECG gating for thoracic CT angiography: a comparative study. AJR Am J Roentgenol 193(4):955–963

    Article  PubMed  Google Scholar 

  8. Hirai N, Horiguchi J, Fujioka C, Kiguchi M, Yamamoto H, Matsuura N, Kitagawa T, Teragawa H, Kohno N, Ito K (2008) Prospective versus retrospective ECG-gated 64-detector coronary CT angiography: assessment of image quality, stenosis, and radiation dose. Radiology 248(2):424–430

    Article  PubMed  Google Scholar 

  9. Earls JP, Berman EL, Urban BA, Curry CA, Lane JL, Jennings RS, McCulloch CC, Hsieh J, Londt JH (2008) Prospectively gated transverse coronary CT angiography versus retrospectively gated helical technique: improved image quality and reduced radiation dose. Radiology 246(3):742–753

    Article  PubMed  Google Scholar 

  10. Pontone G, Andreini D, Bartorelli AL, Cortinovis S, Mushtaq S, Bertella E, Annoni A, Formenti A, Nobili E, Trabattoni D, Montorsi P, Ballerini G, Agostoni P, Pepi M (2009) Diagnostic accuracy of coronary computed tomography angiography: a comparison between prospective and retrospective electrocardiogram triggering. J Am Coll Cardiol 54(4):346–355

    Article  PubMed  Google Scholar 

  11. Efstathopoulos EP, Kelekis NL, Pantos I, Brountzos E, Argentos S, Grebac J, Ziaka D, Katritsis DG, Seimenis I (2009) Reduction of the estimated radiation dose and associated patient risk with prospective ECG-gated 256-slice CT coronary angiography. Phys Med Biol 54(17):5209–5222

    Article  PubMed  CAS  Google Scholar 

  12. Alkadhi H, Stolzmann P, Desbiolles L, Baumueller S, Goetti R, Plass A, Scheffel H, Feuchtner G, Falk V, Marincek B, Leschka S (2010) Low-dose, 128-slice, dual-source CT coronary angiography: accuracy and radiation dose of the high-pitch and the step-and-shoot mode. Heart (British Cardiac Society) 96(12):933–938

    Google Scholar 

  13. Law WY, Yang CC, Chen LK, Huang TC, Lu KM, Wu TH, Mok GS (2011) Retrospective gating versus prospective triggering for noninvasive coronary angiography: assessment of image quality and radiation dose using a 256-slice CT scanner with 270 ms gantry rotation. Acad radiol 18(1):31–39

    Google Scholar 

  14. Buechel RR, Husmann L, Herzog BA, Pazhenkottil AP, Nkoulou R, Ghadri JR, Treyer V, von Schulthess P, Kaufmann PA (2011) Low-dose computed tomography coronary angiography with prospective electrocardiogram triggering feasibility in a large population. J Am Coll Cardiol 57(3):332–336

    Google Scholar 

  15. Herzog BA, Husmann L, Burkhard N, Valenta I, Gaemperli O, Tatsugami F, Wyss CA, Landmesser U, Kaufmann PA (2009) Low-dose CT coronary angiography using prospective ECG-triggering: impact of mean heart rate and heart rate variability on image quality. Acad radiol 16(1):15–21. doi:10.1016/j.acra.2008.06.010

    Article  PubMed  Google Scholar 

  16. Leschka S, Scheffel H, Desbiolles L, Plass A, Gaemperli O, Valenta I, Husmann L, Flohr TG, Genoni M, Marincek B, Kaufmann PA, Alkadhi H (2007) Image quality and reconstruction intervals of dual-source CT coronary angiography: recommendations for ECG-pulsing windowing. Invest Radiol 42(8):543–549

    Article  PubMed  Google Scholar 

  17. Achenbach S, Ropers U, Kuettner A, Anders K, Pflederer T, Komatsu S, Bautz W, Daniel WG, Ropers D (2008) Randomized comparison of 64-slice single- and dual-source computed tomography coronary angiography for the detection of coronary artery disease. J Am Coll Cardiol 1(2):177–186

    Google Scholar 

  18. Bamberg F, Sommer WH, Schenzle JC, Becker CR, Nikolaou K, Reiser MF, Johnson TR (2010) Systolic acquisition of coronary dual-source computed tomography angiography: feasibility in an unselected patient population. Eur radiol 20(6):1331–1336

    Google Scholar 

  19. Wintersperger BJ, Nikolaou K, von Ziegler F, Johnson T, Rist C, Leber A, Flohr T, Knez A, Reiser MF, Becker CR (2006) Image quality, motion artifacts, and reconstruction timing of 64-slice coronary computed tomography angiography with 0.33-second rotation speed. Invest Radiol 41(5):436–442. doi:10.1097/01.rli.0000202639.99949.c6

    Article  PubMed  Google Scholar 

  20. Adler G, Meille L, Rohnean A, Sigal-Cinqualbre A, Capderou A, Paul JF (2010) Robustness of end-systolic reconstructions in coronary dual-source CT angiography for high heart rate patients. Eur Radiol 20(5):1118–1123. doi:10.1007/s00330-009-1642-9

    Article  PubMed  Google Scholar 

  21. Seifarth H, Wienbeck S, Pusken M, Juergens KU, Maintz D, Vahlhaus C, Heindel W, Fischbach R (2007) Optimal systolic and diastolic reconstruction windows for coronary CT angiography using dual-source CT. AJR Am J Roentgenol 189(6):1317–1323

    Article  PubMed  Google Scholar 

  22. Paul JF, Abada HT (2007) Strategies for reduction of radiation dose in cardiac multislice CT. Eur Radiol 17(8):2028–2037. doi:10.1007/s00330-007-0584-3

    Article  PubMed  Google Scholar 

  23. Ghadri JR, Kuest SM, Goetti R, Fiechter M, Pazhenkottil AP, Nkoulou RN, Kuhn FP, Pietsch C, von Schulthess P, Gaemperli O, Templin C, Kaufmann PA (2011) Image quality and radiation dose comparison of prospectively triggered low-dose CCTA: 128-slice dual-source high-pitch spiral versus 64-slice single-source sequential acquisition. Int J Cardiovasc Imaging. doi:10.1007/s10554-011-9921-3

    Google Scholar 

  24. Earls JP (2009) How to use a prospective gated technique for cardiac CT. J cardiovasc comput tomogr 3(1):45–51. doi:10.1016/j.jcct.2008.10.013

    Article  PubMed  Google Scholar 

  25. Paul JF, Rohnean A, Elfassy E, Sigal-Cinqualbre A (2011) Radiation dose for thoracic and coronary step-and-shoot CT using a 128-slice dual-source machine in infants and small children with congenital heart disease. Pediatr Radiol 41(2):244–249. doi:10.1007/s00247-010-1804-6

    Article  PubMed  Google Scholar 

  26. Hsiao EM, Rybicki FJ, Steigner M (2010) CT coronary angiography: 256-slice and 320-detector row scanners. Curr cardiol rep 12(1):68–75. doi:10.1007/s11886-009-0075-z

    Article  PubMed  Google Scholar 

  27. Rybicki FJ, Otero HJ, Steigner ML, Vorobiof G, Nallamshetty L, Mitsouras D, Ersoy H, Mather RT, Judy PF, Cai T, Coyner K, Schultz K, Whitmore AG, Di Carli MF (2008) Initial evaluation of coronary images from 320-detector row computed tomography. Int J Cardiovasc Imaging 24(5):535–546. doi:10.1007/s10554-008-9308-2

    Article  PubMed  Google Scholar 

  28. Steigner ML, Otero HJ, Cai T, Mitsouras D, Nallamshetty L, Whitmore AG, Ersoy H, Levit NA, Di Carli MF, Rybicki FJ (2009) Narrowing the phase window width in prospectively ECG-gated single heart beat 320-detector row coronary CT angiography. Int J Cardiovasc Imaging 25(1):85–90. doi:10.1007/s10554-008-9347-8

    Article  PubMed  Google Scholar 

  29. Sun G, Li M, Jiang XS, Li L, Peng ZH, Li GY, Xu L (2012) 320-detector row CT coronary angiography: effects of heart rate and heart rate variability on image quality, diagnostic accuracy and radiation exposure. Br j radiol. doi:10.1259/bjr/92160185

    Google Scholar 

  30. Sun G, Li M, Li L, Li GY, Zhang H, Peng ZH (2011) Optimal systolic and diastolic reconstruction windows for coronary CT angiography using 320-detector rows dynamic volume CT. Clin Radiol 66(7):614–620. doi:10.1016/j.crad.2011.02.007

    Article  PubMed  CAS  Google Scholar 

  31. Husmann L, Herzog BA, Burkhard N, Tatsugami F, Valenta I, Gaemperli O, Wyss CA, Landmesser U, Kaufmann PA (2009) Body physique and heart rate variability determine the occurrence of stair-step artefacts in 64-slice CT coronary angiography with prospective ECG-triggering. Eur Radiol 19(7):1698–1703

    Article  PubMed  Google Scholar 

  32. Coles DR, Smail MA, Negus IS, Wilde P, Oberhoff M, Karsch KR, Baumbach A (2006) Comparison of radiation doses from multislice computed tomography coronary angiography and conventional diagnostic angiography. J Am Coll Cardiol 47(9):1840–1845. doi:10.1016/j.jacc.2005.11.078

    Article  PubMed  Google Scholar 

  33. Pugliese F, Hunink MG, Gruszczynska K, Alberghina F, Malago R, van Pelt N, Mollet NR, Cademartiri F, Weustink AC, Meijboom WB, Witteman CL, de Feyter PJ, Krestin GP (2009) Learning curve for coronary CT angiography: what constitutes sufficient training? Radiology 251(2):359–368

    Article  PubMed  Google Scholar 

  34. Zhu X, Chen W, Li M, Xu Y, Xu H, Zhu Y, Wang D, Tang L (2011) Contrast material injection protocol with the flow rate adjusted to the heart rate for dual source CT coronary angiography. Int J Cardiovasc Imaging. doi:10.1007/s10554-011-9950-y

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Paul, JF., Amato, A. & Rohnean, A. Low-dose coronary-CT angiography using step and shoot at any heart rate: comparison of image quality at systole for high heart rate and diastole for low heart rate with a 128-slice dual-source machine. Int J Cardiovasc Imaging 29, 651–657 (2013). https://doi.org/10.1007/s10554-012-0110-9

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